Anti-VWC2L functional antibody

Anti-VWC2L functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to VWC2L/VWC2L products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1368-Ab-1/ GM-Tg-hg-SE1368-Ab-2Anti-Human VWC2L monoclonal antibodyHuman
GM-Tg-rg-SE1368-Ab-1/ GM-Tg-rg-SE1368-Ab-2Anti-Rat VWC2L monoclonal antibodyRat
GM-Tg-mg-SE1368-Ab-1/ GM-Tg-mg-SE1368-Ab-2Anti-Mouse VWC2L monoclonal antibodyMouse
GM-Tg-cynog-SE1368-Ab-1/ GM-Tg-cynog-SE1368-Ab-2Anti-Cynomolgus/ Rhesus macaque VWC2L monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1368-Ab-1/ GM-Tg-felg-SE1368-Ab-2Anti-Feline VWC2L monoclonal antibodyFeline
GM-Tg-cang-SE1368-Ab-1/ GM-Tg-cang-SE1368-Ab-2Anti-Canine VWC2L monoclonal antibodyCanine
GM-Tg-bovg-SE1368-Ab-1/ GM-Tg-bovg-SE1368-Ab-2Anti-Bovine VWC2L monoclonal antibodyBovine
GM-Tg-equg-SE1368-Ab-1/ GM-Tg-equg-SE1368-Ab-2Anti-Equine VWC2L monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1368-Ab-1/ GM-Tg-hg-SE1368-Ab-2; GM-Tg-rg-SE1368-Ab-1/ GM-Tg-rg-SE1368-Ab-2;
GM-Tg-mg-SE1368-Ab-1/ GM-Tg-mg-SE1368-Ab-2; GM-Tg-cynog-SE1368-Ab-1/ GM-Tg-cynog-SE1368-Ab-2;
GM-Tg-felg-SE1368-Ab-1/ GM-Tg-felg-SE1368-Ab-2; GM-Tg-cang-SE1368-Ab-1/ GM-Tg-cang-SE1368-Ab-2;
GM-Tg-bovg-SE1368-Ab-1/ GM-Tg-bovg-SE1368-Ab-2; GM-Tg-equg-SE1368-Ab-1/ GM-Tg-equg-SE1368-Ab-2
Products NameAnti-VWC2L monoclonal antibody
Formatmab
Target NameVWC2L
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-VWC2L benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1368-Ag-1Recombinant multi-species VWC2L protein


    Target information

    Target IDGM-SE1368
    Target NameVWC2L
    Gene ID402117,320460,501160,694511,119867952,101080473,782360,100050385
    Gene Symbol and SynonymsA830006F12Rik,Brl,RGD1565501,VWC2L
    Uniprot AccessionB2RUY7
    Uniprot Entry NameVWC2L_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000174453
    Target ClassificationN/A

    The target: VWC2L, gene name: VWC2L, also named as . Predicted to be involved in negative regulation of BMP signaling pathway. Predicted to act upstream of or within positive regulation of neuron differentiation. Predicted to be located in extracellular region and synapse. Predicted to be part of AMPA glutamate receptor complex. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.