Anti-VWDE functional antibody

Anti-VWDE functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to VWDE/VWDE products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1370-Ab-1/ GM-Tg-hg-SE1370-Ab-2Anti-Human VWDE monoclonal antibodyHuman
GM-Tg-rg-SE1370-Ab-1/ GM-Tg-rg-SE1370-Ab-2Anti-Rat VWDE monoclonal antibodyRat
GM-Tg-mg-SE1370-Ab-1/ GM-Tg-mg-SE1370-Ab-2Anti-Mouse VWDE monoclonal antibodyMouse
GM-Tg-cynog-SE1370-Ab-1/ GM-Tg-cynog-SE1370-Ab-2Anti-Cynomolgus/ Rhesus macaque VWDE monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1370-Ab-1/ GM-Tg-felg-SE1370-Ab-2Anti-Feline VWDE monoclonal antibodyFeline
GM-Tg-cang-SE1370-Ab-1/ GM-Tg-cang-SE1370-Ab-2Anti-Canine VWDE monoclonal antibodyCanine
GM-Tg-bovg-SE1370-Ab-1/ GM-Tg-bovg-SE1370-Ab-2Anti-Bovine VWDE monoclonal antibodyBovine
GM-Tg-equg-SE1370-Ab-1/ GM-Tg-equg-SE1370-Ab-2Anti-Equine VWDE monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1370-Ab-1/ GM-Tg-hg-SE1370-Ab-2; GM-Tg-rg-SE1370-Ab-1/ GM-Tg-rg-SE1370-Ab-2;
GM-Tg-mg-SE1370-Ab-1/ GM-Tg-mg-SE1370-Ab-2; GM-Tg-cynog-SE1370-Ab-1/ GM-Tg-cynog-SE1370-Ab-2;
GM-Tg-felg-SE1370-Ab-1/ GM-Tg-felg-SE1370-Ab-2; GM-Tg-cang-SE1370-Ab-1/ GM-Tg-cang-SE1370-Ab-2;
GM-Tg-bovg-SE1370-Ab-1/ GM-Tg-bovg-SE1370-Ab-2; GM-Tg-equg-SE1370-Ab-1/ GM-Tg-equg-SE1370-Ab-2
Products NameAnti-VWDE monoclonal antibody
Formatmab
Target NameVWDE
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-VWDE benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1370-Ag-1Recombinant multi-species VWDE protein


    Target information

    Target IDGM-SE1370
    Target NameVWDE
    Gene ID221806,232585,502731,482323,105259791,100301009,100065013
    Gene Symbol and SynonymsGm467,RGD1561223,VWDE
    Uniprot AccessionQ8N2E2
    Uniprot Entry NameVWDE_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000146530
    Target ClassificationN/A

    The target: VWDE, gene name: VWDE, also named as . Predicted to enable signaling receptor binding activity. Predicted to be involved in anatomical structure development. Predicted to be active in cell surface and extracellular region. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.