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Anti-WFDC1/ PS20 functional antibody
Anti-WFDC1/ PS20 functional antibody for cell culture, ELISA & in-vivo assay
Go to WFDC1/WFDC1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1372-Ab-1/ GM-Tg-hg-SE1372-Ab-2 | Anti-Human WFDC1 monoclonal antibody | Human |
| GM-Tg-rg-SE1372-Ab-1/ GM-Tg-rg-SE1372-Ab-2 | Anti-Rat WFDC1 monoclonal antibody | Rat |
| GM-Tg-mg-SE1372-Ab-1/ GM-Tg-mg-SE1372-Ab-2 | Anti-Mouse WFDC1 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1372-Ab-1/ GM-Tg-cynog-SE1372-Ab-2 | Anti-Cynomolgus/ Rhesus macaque WFDC1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1372-Ab-1/ GM-Tg-felg-SE1372-Ab-2 | Anti-Feline WFDC1 monoclonal antibody | Feline |
| GM-Tg-cang-SE1372-Ab-1/ GM-Tg-cang-SE1372-Ab-2 | Anti-Canine WFDC1 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1372-Ab-1/ GM-Tg-bovg-SE1372-Ab-2 | Anti-Bovine WFDC1 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1372-Ab-1/ GM-Tg-equg-SE1372-Ab-2 | Anti-Equine WFDC1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1372-Ab-1/ GM-Tg-hg-SE1372-Ab-2; GM-Tg-rg-SE1372-Ab-1/ GM-Tg-rg-SE1372-Ab-2; GM-Tg-mg-SE1372-Ab-1/ GM-Tg-mg-SE1372-Ab-2; GM-Tg-cynog-SE1372-Ab-1/ GM-Tg-cynog-SE1372-Ab-2; GM-Tg-felg-SE1372-Ab-1/ GM-Tg-felg-SE1372-Ab-2; GM-Tg-cang-SE1372-Ab-1/ GM-Tg-cang-SE1372-Ab-2; GM-Tg-bovg-SE1372-Ab-1/ GM-Tg-bovg-SE1372-Ab-2; GM-Tg-equg-SE1372-Ab-1/ GM-Tg-equg-SE1372-Ab-2 |
| Products Name | Anti-WFDC1 monoclonal antibody |
| Format | mab |
| Target Name | WFDC1 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-WFDC1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1372-Ag-1 | Recombinant multi-species WFDC1/ PS20 protein |
Target information
| Target ID | GM-SE1372 |
| Target Name | WFDC1 |
| Gene ID | 58189,67866,171112,715230,489682,101088637,505366,100070154 |
| Gene Symbol and Synonyms | 2310058A03Rik,PS20,WFDC1 |
| Uniprot Accession | Q9HC57,O70280 |
| Uniprot Entry Name | WFDC1_HUMAN,WFDC1_RAT |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000103175 |
| Target Classification | N/A |
The target: WFDC1, gene name: WFDC1, also named as PS20. This gene encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is mapped to chromosome 16q24, an area of frequent loss of heterozygosity in cancers, including prostate, breast and hepatocellular cancers and Wilms' tumor. This gene is downregulated in many cancer types and may be involved in the inhibition of cell proliferation. The encoded protein may also play a role in the susceptibility of certain CD4 memory T cells to human immunodeficiency virus infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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