Anti-WFD13/ WFDC13/ C20orf138 functional antibody

Anti-WFD13/ WFDC13/ C20orf138 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to WFDC13/WFDC13 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1375-Ab-1/ GM-Tg-hg-SE1375-Ab-2Anti-Human WFDC13 monoclonal antibodyHuman
GM-Tg-rg-SE1375-Ab-1/ GM-Tg-rg-SE1375-Ab-2Anti-Rat WFDC13 monoclonal antibodyRat
GM-Tg-mg-SE1375-Ab-1/ GM-Tg-mg-SE1375-Ab-2Anti-Mouse WFDC13 monoclonal antibodyMouse
GM-Tg-cynog-SE1375-Ab-1/ GM-Tg-cynog-SE1375-Ab-2Anti-Cynomolgus/ Rhesus macaque WFDC13 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1375-Ab-1/ GM-Tg-felg-SE1375-Ab-2Anti-Feline WFDC13 monoclonal antibodyFeline
GM-Tg-cang-SE1375-Ab-1/ GM-Tg-cang-SE1375-Ab-2Anti-Canine WFDC13 monoclonal antibodyCanine
GM-Tg-bovg-SE1375-Ab-1/ GM-Tg-bovg-SE1375-Ab-2Anti-Bovine WFDC13 monoclonal antibodyBovine
GM-Tg-equg-SE1375-Ab-1/ GM-Tg-equg-SE1375-Ab-2Anti-Equine WFDC13 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1375-Ab-1/ GM-Tg-hg-SE1375-Ab-2; GM-Tg-rg-SE1375-Ab-1/ GM-Tg-rg-SE1375-Ab-2;
GM-Tg-mg-SE1375-Ab-1/ GM-Tg-mg-SE1375-Ab-2; GM-Tg-cynog-SE1375-Ab-1/ GM-Tg-cynog-SE1375-Ab-2;
GM-Tg-felg-SE1375-Ab-1/ GM-Tg-felg-SE1375-Ab-2; GM-Tg-cang-SE1375-Ab-1/ GM-Tg-cang-SE1375-Ab-2;
GM-Tg-bovg-SE1375-Ab-1/ GM-Tg-bovg-SE1375-Ab-2; GM-Tg-equg-SE1375-Ab-1/ GM-Tg-equg-SE1375-Ab-2
Products NameAnti-WFDC13 monoclonal antibody
Formatmab
Target NameWFDC13
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-WFDC13 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1375-Ag-1Recombinant multi-species WFD13/ WFDC13/ C20orf138 protein


    Target information

    Target IDGM-SE1375
    Target NameWFDC13
    Gene ID164237,408190,100365199,717327,106557665,101086892,101907910,100630229
    Gene Symbol and SynonymsC20orf138,dJ601O1.3,WAP13,WFDC13,Wfdc13l1
    Uniprot AccessionQ8IUB5
    Uniprot Entry NameWFD13_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000168634
    Target ClassificationN/A

    The target: WFDC13, gene name: WFDC13, also named as C20orf138, WAP13, dJ601O1.3. This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the telomeric cluster. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.