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Anti-WFDC5/ PRG5/ WAP1 functional antibody
Anti-WFDC5/ PRG5/ WAP1 functional antibody for cell culture, ELISA & in-vivo assay
Go to WFDC5/WFDC5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1377-Ab-1/ GM-Tg-hg-SE1377-Ab-2 | Anti-Human WFDC5 monoclonal antibody | Human |
| GM-Tg-rg-SE1377-Ab-1/ GM-Tg-rg-SE1377-Ab-2 | Anti-Rat WFDC5 monoclonal antibody | Rat |
| GM-Tg-mg-SE1377-Ab-1/ GM-Tg-mg-SE1377-Ab-2 | Anti-Mouse WFDC5 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1377-Ab-1/ GM-Tg-cynog-SE1377-Ab-2 | Anti-Cynomolgus/ Rhesus macaque WFDC5 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1377-Ab-1/ GM-Tg-felg-SE1377-Ab-2 | Anti-Feline WFDC5 monoclonal antibody | Feline |
| GM-Tg-cang-SE1377-Ab-1/ GM-Tg-cang-SE1377-Ab-2 | Anti-Canine WFDC5 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1377-Ab-1/ GM-Tg-bovg-SE1377-Ab-2 | Anti-Bovine WFDC5 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1377-Ab-1/ GM-Tg-equg-SE1377-Ab-2 | Anti-Equine WFDC5 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1377-Ab-1/ GM-Tg-hg-SE1377-Ab-2; GM-Tg-rg-SE1377-Ab-1/ GM-Tg-rg-SE1377-Ab-2; GM-Tg-mg-SE1377-Ab-1/ GM-Tg-mg-SE1377-Ab-2; GM-Tg-cynog-SE1377-Ab-1/ GM-Tg-cynog-SE1377-Ab-2; GM-Tg-felg-SE1377-Ab-1/ GM-Tg-felg-SE1377-Ab-2; GM-Tg-cang-SE1377-Ab-1/ GM-Tg-cang-SE1377-Ab-2; GM-Tg-bovg-SE1377-Ab-1/ GM-Tg-bovg-SE1377-Ab-2; GM-Tg-equg-SE1377-Ab-1/ GM-Tg-equg-SE1377-Ab-2 |
| Products Name | Anti-WFDC5 monoclonal antibody |
| Format | mab |
| Target Name | WFDC5 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-WFDC5 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1377-Ag-1 | Recombinant multi-species WFDC5/ PRG5/ WAP1 protein |
Target information
| Target ID | GM-SE1377 |
| Target Name | WFDC5 |
| Gene ID | 149708,296352,711627,610999,101089430,517054,100070884 |
| Gene Symbol and Synonyms | dJ211D12.5,PRG5,WAP1,WFDC5 |
| Uniprot Accession | Q8TCV5,A4K2T2 |
| Uniprot Entry Name | WFDC5_HUMAN,WFDC5_MACMU |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000175121 |
| Target Classification | N/A |
The target: WFDC5, gene name: WFDC5, also named as PRG5, WAP1, dJ211D12.5. This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. Most WFDC proteins contain only one WFDC domain, and this encoded protein contains two WFDC domains. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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