Anti-WFKN1/ WFIKKN1/ C16orf12 functional antibody

Anti-WFKN1/ WFIKKN1/ C16orf12 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to WFIKKN1/WFIKKN1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1380-Ab-1/ GM-Tg-hg-SE1380-Ab-2Anti-Human WFIKKN1 monoclonal antibodyHuman
GM-Tg-rg-SE1380-Ab-1/ GM-Tg-rg-SE1380-Ab-2Anti-Rat WFIKKN1 monoclonal antibodyRat
GM-Tg-mg-SE1380-Ab-1/ GM-Tg-mg-SE1380-Ab-2Anti-Mouse WFIKKN1 monoclonal antibodyMouse
GM-Tg-cynog-SE1380-Ab-1/ GM-Tg-cynog-SE1380-Ab-2Anti-Cynomolgus/ Rhesus macaque WFIKKN1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1380-Ab-1/ GM-Tg-felg-SE1380-Ab-2Anti-Feline WFIKKN1 monoclonal antibodyFeline
GM-Tg-cang-SE1380-Ab-1/ GM-Tg-cang-SE1380-Ab-2Anti-Canine WFIKKN1 monoclonal antibodyCanine
GM-Tg-bovg-SE1380-Ab-1/ GM-Tg-bovg-SE1380-Ab-2Anti-Bovine WFIKKN1 monoclonal antibodyBovine
GM-Tg-equg-SE1380-Ab-1/ GM-Tg-equg-SE1380-Ab-2Anti-Equine WFIKKN1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1380-Ab-1/ GM-Tg-hg-SE1380-Ab-2; GM-Tg-rg-SE1380-Ab-1/ GM-Tg-rg-SE1380-Ab-2;
GM-Tg-mg-SE1380-Ab-1/ GM-Tg-mg-SE1380-Ab-2; GM-Tg-cynog-SE1380-Ab-1/ GM-Tg-cynog-SE1380-Ab-2;
GM-Tg-felg-SE1380-Ab-1/ GM-Tg-felg-SE1380-Ab-2; GM-Tg-cang-SE1380-Ab-1/ GM-Tg-cang-SE1380-Ab-2;
GM-Tg-bovg-SE1380-Ab-1/ GM-Tg-bovg-SE1380-Ab-2; GM-Tg-equg-SE1380-Ab-1/ GM-Tg-equg-SE1380-Ab-2
Products NameAnti-WFIKKN1 monoclonal antibody
Formatmab
Target NameWFIKKN1
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-WFIKKN1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1380-Ag-1Recombinant multi-species WFKN1/ WFIKKN1/ C16orf12 protein


    Target information

    Target IDGM-SE1380
    Target NameWFIKKN1
    Gene ID117166,215001,363555,722338,490094,101094072,540233,100066872
    Gene Symbol and SynonymsC16orf12,Gasp2,Oc29,RGD1565835,RJD2,WFDC20A,WFIKKN,WFIKKN1
    Uniprot AccessionQ96NZ8,P0C5J5
    Uniprot Entry NameWFKN1_HUMAN,WFKN1_RAT
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000127578
    Target ClassificationN/A

    The target: WFIKKN1, gene name: WFIKKN1, also named as C16orf12, RJD2, WFDC20A, WFIKKN. This gene encodes a secreted multidomain protein consisting of a signal peptide, a WAP domain, a follistatin domain, an immunoglobulin domain, two tandem Kunitz domains, and an NTR domain. These domains have been implicated frequently in inhibition of various types of proteases, suggesting that the encoded protein may be a multivalent protease inhibitor and may control the action of multiple types of serine proteases as well as metalloproteinases. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.