Anti-MMP27/ MMP-27 functional antibody

Anti-MMP27/ MMP-27 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to MMP27/MMP27 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1391-Ab-1/ GM-Tg-hg-SE1391-Ab-2Anti-Human MMP27 monoclonal antibodyHuman
GM-Tg-rg-SE1391-Ab-1/ GM-Tg-rg-SE1391-Ab-2Anti-Rat MMP27 monoclonal antibodyRat
GM-Tg-mg-SE1391-Ab-1/ GM-Tg-mg-SE1391-Ab-2Anti-Mouse MMP27 monoclonal antibodyMouse
GM-Tg-cynog-SE1391-Ab-1/ GM-Tg-cynog-SE1391-Ab-2Anti-Cynomolgus/ Rhesus macaque MMP27 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1391-Ab-1/ GM-Tg-felg-SE1391-Ab-2Anti-Feline MMP27 monoclonal antibodyFeline
GM-Tg-cang-SE1391-Ab-1/ GM-Tg-cang-SE1391-Ab-2Anti-Canine MMP27 monoclonal antibodyCanine
GM-Tg-bovg-SE1391-Ab-1/ GM-Tg-bovg-SE1391-Ab-2Anti-Bovine MMP27 monoclonal antibodyBovine
GM-Tg-equg-SE1391-Ab-1/ GM-Tg-equg-SE1391-Ab-2Anti-Equine MMP27 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1391-Ab-1/ GM-Tg-hg-SE1391-Ab-2; GM-Tg-rg-SE1391-Ab-1/ GM-Tg-rg-SE1391-Ab-2;
GM-Tg-mg-SE1391-Ab-1/ GM-Tg-mg-SE1391-Ab-2; GM-Tg-cynog-SE1391-Ab-1/ GM-Tg-cynog-SE1391-Ab-2;
GM-Tg-felg-SE1391-Ab-1/ GM-Tg-felg-SE1391-Ab-2; GM-Tg-cang-SE1391-Ab-1/ GM-Tg-cang-SE1391-Ab-2;
GM-Tg-bovg-SE1391-Ab-1/ GM-Tg-bovg-SE1391-Ab-2; GM-Tg-equg-SE1391-Ab-1/ GM-Tg-equg-SE1391-Ab-2
Products NameAnti-MMP27 monoclonal antibody
Formatmab
Target NameMMP27
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-MMP27 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1391-Ag-1Recombinant multi-species MMP27/ MMP-27 protein


    Target information

    Target IDGM-SE1391
    Target NameMMP27
    Gene ID64066,234911,300340,703307,489430,101083699,518487,100068996
    Gene Symbol and SynonymsGm180,MMP-27,MMP27
    Uniprot AccessionQ9H306
    Uniprot Entry NameMMP27_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000137675
    Target ClassificationN/A

    The target: MMP27, gene name: MMP27, also named as MMP-27. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.