Anti-PLPL4/ PNPLA4/ DXS1283E functional antibody

Anti-PLPL4/ PNPLA4/ DXS1283E functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to PNPLA4/PNPLA4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1399-Ab-1/ GM-Tg-hg-SE1399-Ab-2Anti-Human PNPLA4 monoclonal antibodyHuman
GM-Tg-rg-SE1399-Ab-1/ GM-Tg-rg-SE1399-Ab-2Anti-Rat PNPLA4 monoclonal antibodyRat
GM-Tg-mg-SE1399-Ab-1/ GM-Tg-mg-SE1399-Ab-2Anti-Mouse PNPLA4 monoclonal antibodyMouse
GM-Tg-cynog-SE1399-Ab-1/ GM-Tg-cynog-SE1399-Ab-2Anti-Cynomolgus/ Rhesus macaque PNPLA4 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1399-Ab-1/ GM-Tg-felg-SE1399-Ab-2Anti-Feline PNPLA4 monoclonal antibodyFeline
GM-Tg-cang-SE1399-Ab-1/ GM-Tg-cang-SE1399-Ab-2Anti-Canine PNPLA4 monoclonal antibodyCanine
GM-Tg-bovg-SE1399-Ab-1/ GM-Tg-bovg-SE1399-Ab-2Anti-Bovine PNPLA4 monoclonal antibodyBovine
GM-Tg-equg-SE1399-Ab-1/ GM-Tg-equg-SE1399-Ab-2Anti-Equine PNPLA4 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1399-Ab-1/ GM-Tg-hg-SE1399-Ab-2; GM-Tg-rg-SE1399-Ab-1/ GM-Tg-rg-SE1399-Ab-2;
GM-Tg-mg-SE1399-Ab-1/ GM-Tg-mg-SE1399-Ab-2; GM-Tg-cynog-SE1399-Ab-1/ GM-Tg-cynog-SE1399-Ab-2;
GM-Tg-felg-SE1399-Ab-1/ GM-Tg-felg-SE1399-Ab-2; GM-Tg-cang-SE1399-Ab-1/ GM-Tg-cang-SE1399-Ab-2;
GM-Tg-bovg-SE1399-Ab-1/ GM-Tg-bovg-SE1399-Ab-2; GM-Tg-equg-SE1399-Ab-1/ GM-Tg-equg-SE1399-Ab-2
Products NameAnti-PNPLA4 monoclonal antibody
Formatmab
Target NamePNPLA4
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PNPLA4 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1399-Ag-1Recombinant multi-species PLPL4/ PNPLA4/ DXS1283E protein


    Target information

    Target IDGM-SE1399
    Target NamePNPLA4
    Gene ID8228,363471,708139,491729,101083743,785567,100050789
    Gene Symbol and SynonymsDXS1283E,GS2,iPLA2eta,PNPLA4,RGD1562200
    Uniprot AccessionP41247
    Uniprot Entry NamePLPL4_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000006757
    Target ClassificationN/A

    The target: PNPLA4, gene name: PNPLA4, also named as DXS1283E, GS2, iPLA2eta. This gene encodes a member of the patatin-like family of phospholipases. The encoded enzyme has both triacylglycerol lipase and transacylase activities and may be involved in adipocyte triglyceride homeostasis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome Y. [provided by RefSeq, Feb 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.