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Anti-TTC19/ 2010204O13Rik/ MC3DN2 functional antibody
Anti-TTC19/ 2010204O13Rik/ MC3DN2 functional antibody for cell culture, ELISA & in-vivo assay
Go to TTC19/TTC19 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1401-Ab-1/ GM-Tg-hg-SE1401-Ab-2 | Anti-Human TTC19 monoclonal antibody | Human |
| GM-Tg-rg-SE1401-Ab-1/ GM-Tg-rg-SE1401-Ab-2 | Anti-Rat TTC19 monoclonal antibody | Rat |
| GM-Tg-mg-SE1401-Ab-1/ GM-Tg-mg-SE1401-Ab-2 | Anti-Mouse TTC19 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1401-Ab-1/ GM-Tg-cynog-SE1401-Ab-2 | Anti-Cynomolgus/ Rhesus macaque TTC19 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1401-Ab-1/ GM-Tg-felg-SE1401-Ab-2 | Anti-Feline TTC19 monoclonal antibody | Feline |
| GM-Tg-cang-SE1401-Ab-1/ GM-Tg-cang-SE1401-Ab-2 | Anti-Canine TTC19 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1401-Ab-1/ GM-Tg-bovg-SE1401-Ab-2 | Anti-Bovine TTC19 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1401-Ab-1/ GM-Tg-equg-SE1401-Ab-2 | Anti-Equine TTC19 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1401-Ab-1/ GM-Tg-hg-SE1401-Ab-2; GM-Tg-rg-SE1401-Ab-1/ GM-Tg-rg-SE1401-Ab-2; GM-Tg-mg-SE1401-Ab-1/ GM-Tg-mg-SE1401-Ab-2; GM-Tg-cynog-SE1401-Ab-1/ GM-Tg-cynog-SE1401-Ab-2; GM-Tg-felg-SE1401-Ab-1/ GM-Tg-felg-SE1401-Ab-2; GM-Tg-cang-SE1401-Ab-1/ GM-Tg-cang-SE1401-Ab-2; GM-Tg-bovg-SE1401-Ab-1/ GM-Tg-bovg-SE1401-Ab-2; GM-Tg-equg-SE1401-Ab-1/ GM-Tg-equg-SE1401-Ab-2 |
| Products Name | Anti-TTC19 monoclonal antibody |
| Format | mab |
| Target Name | TTC19 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-TTC19 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1401-Ag-1 | Recombinant multi-species TTC19/ 2010204O13Rik/ MC3DN2 protein |
Target information
| Target ID | GM-SE1401 |
| Target Name | TTC19 |
| Gene ID | 54902,72795,691506,700653,479516,101083219,789903,100073148 |
| Gene Symbol and Synonyms | 2010204O13Rik,2810460C24Rik,MC3DN2,RGD1311797,TTC19 |
| Uniprot Accession | Q6DKK2,D4A6D7 |
| Uniprot Entry Name | TTC19_HUMAN,TTC19_RAT |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000011295 |
| Target Classification | N/A |
The target: TTC19, gene name: TTC19, also named as 2010204O13Rik, MC3DN2. This gene encodes a protein with a tetratricopeptide repeat (TPR) domain containing several TPRs of about 34 aa each. These repeats are found in a variety of organisms including bacteria, fungi and plants, and are involved in a variety of functions including protein-protein interactions. This protein is embedded in the inner mitochondrial membrane and is involved in the formation of the mitochondrial respiratory chain III. It has also been suggested that this protein plays a role in cytokinesis. Mutations in this gene cause mitochondrial complex III deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2012].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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