- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-DHX8/ DDX8/ Dhr2 functional antibody
Anti-DHX8/ DDX8/ Dhr2 functional antibody for cell culture, ELISA & in-vivo assay
Go to DHX8/DHX8 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1414-Ab-1/ GM-Tg-hg-SE1414-Ab-2 | Anti-Human DHX8 monoclonal antibody | Human |
| GM-Tg-rg-SE1414-Ab-1/ GM-Tg-rg-SE1414-Ab-2 | Anti-Rat DHX8 monoclonal antibody | Rat |
| GM-Tg-mg-SE1414-Ab-1/ GM-Tg-mg-SE1414-Ab-2 | Anti-Mouse DHX8 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1414-Ab-1/ GM-Tg-cynog-SE1414-Ab-2 | Anti-Cynomolgus/ Rhesus macaque DHX8 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1414-Ab-1/ GM-Tg-felg-SE1414-Ab-2 | Anti-Feline DHX8 monoclonal antibody | Feline |
| GM-Tg-cang-SE1414-Ab-1/ GM-Tg-cang-SE1414-Ab-2 | Anti-Canine DHX8 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1414-Ab-1/ GM-Tg-bovg-SE1414-Ab-2 | Anti-Bovine DHX8 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1414-Ab-1/ GM-Tg-equg-SE1414-Ab-2 | Anti-Equine DHX8 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1414-Ab-1/ GM-Tg-hg-SE1414-Ab-2; GM-Tg-rg-SE1414-Ab-1/ GM-Tg-rg-SE1414-Ab-2; GM-Tg-mg-SE1414-Ab-1/ GM-Tg-mg-SE1414-Ab-2; GM-Tg-cynog-SE1414-Ab-1/ GM-Tg-cynog-SE1414-Ab-2; GM-Tg-felg-SE1414-Ab-1/ GM-Tg-felg-SE1414-Ab-2; GM-Tg-cang-SE1414-Ab-1/ GM-Tg-cang-SE1414-Ab-2; GM-Tg-bovg-SE1414-Ab-1/ GM-Tg-bovg-SE1414-Ab-2; GM-Tg-equg-SE1414-Ab-1/ GM-Tg-equg-SE1414-Ab-2 |
| Products Name | Anti-DHX8 monoclonal antibody |
| Format | mab |
| Target Name | DHX8 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-DHX8 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1414-Ag-1 | Recombinant multi-species DHX8/ DDX8/ Dhr2 protein |
Target information
| Target ID | GM-SE1414 |
| Target Name | DHX8 |
| Gene ID | 1659,217207,287727,713228,480507,101094639,536093,100051804 |
| Gene Symbol and Synonyms | DDX8,Dhr2,DHX8,HRH1,LRRGT00035,mDEAH6,mKIAA4096,PRP22,PRPF22 |
| Uniprot Accession | Q14562 |
| Uniprot Entry Name | DHX8_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000067596 |
| Target Classification | N/A |
The target: DHX8, gene name: DHX8, also named as DDX8, Dhr2, HRH1, PRP22, PRPF22. This gene is a member of the DEAH box polypeptide family. The encoded protein contains the DEAH (Asp-Glu-Ala-His) motif which is characteristic of all DEAH box proteins, and is thought to function as an ATP-dependent RNA helicase that regulates the release of spliced mRNAs from spliceosomes prior to their export from the nucleus. This protein may be required for the replication of human immunodeficiency virus type 1 (HIV-1). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
