- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-ERLEC/ ERLEC1/ C2orf30 functional antibody
Anti-ERLEC/ ERLEC1/ C2orf30 functional antibody for cell culture, ELISA & in-vivo assay
Go to ERLEC1/ERLEC1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1415-Ab-1/ GM-Tg-hg-SE1415-Ab-2 | Anti-Human ERLEC1 monoclonal antibody | Human |
| GM-Tg-rg-SE1415-Ab-1/ GM-Tg-rg-SE1415-Ab-2 | Anti-Rat ERLEC1 monoclonal antibody | Rat |
| GM-Tg-mg-SE1415-Ab-1/ GM-Tg-mg-SE1415-Ab-2 | Anti-Mouse ERLEC1 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1415-Ab-1/ GM-Tg-cynog-SE1415-Ab-2 | Anti-Cynomolgus/ Rhesus macaque ERLEC1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1415-Ab-1/ GM-Tg-felg-SE1415-Ab-2 | Anti-Feline ERLEC1 monoclonal antibody | Feline |
| GM-Tg-cang-SE1415-Ab-1/ GM-Tg-cang-SE1415-Ab-2 | Anti-Canine ERLEC1 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1415-Ab-1/ GM-Tg-bovg-SE1415-Ab-2 | Anti-Bovine ERLEC1 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1415-Ab-1/ GM-Tg-equg-SE1415-Ab-2 | Anti-Equine ERLEC1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1415-Ab-1/ GM-Tg-hg-SE1415-Ab-2; GM-Tg-rg-SE1415-Ab-1/ GM-Tg-rg-SE1415-Ab-2; GM-Tg-mg-SE1415-Ab-1/ GM-Tg-mg-SE1415-Ab-2; GM-Tg-cynog-SE1415-Ab-1/ GM-Tg-cynog-SE1415-Ab-2; GM-Tg-felg-SE1415-Ab-1/ GM-Tg-felg-SE1415-Ab-2; GM-Tg-cang-SE1415-Ab-1/ GM-Tg-cang-SE1415-Ab-2; GM-Tg-bovg-SE1415-Ab-1/ GM-Tg-bovg-SE1415-Ab-2; GM-Tg-equg-SE1415-Ab-1/ GM-Tg-equg-SE1415-Ab-2 |
| Products Name | Anti-ERLEC1 monoclonal antibody |
| Format | mab |
| Target Name | ERLEC1 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-ERLEC1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1415-Ag-1 | Recombinant multi-species ERLEC/ ERLEC1/ C2orf30 protein |
| ORF Viral Vector | vGMLP003165 | human ERLEC1 Lentivirus particle |
| ORF Viral Vector | pGMLP003165 | human ERLEC1 Lentivirus plasmid |
| ORF Viral Vector | pGMLV000530 | human ERLEC1 Lentivirus plasmid |
| ORF Viral Vector | vGMLV000530 | human ERLEC1 Lentivirus particle |
| ORF Viral Vector | pGMLPm002967 | mouse Erlec1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm002967 | mouse Erlec1 Lentivirus particle |
Target information
| Target ID | GM-SE1415 |
| Target Name | ERLEC1 |
| Gene ID | 27248,66753,289874,716460,474593,101089431,781454,100067003 |
| Gene Symbol and Synonyms | 4933407N01Rik,C2orf30,CIM,CL24936,CL25084,ERLEC1,HEL117,RGD1306508,XTP3-B,XTP3TPB |
| Uniprot Accession | Q96DZ1 |
| Uniprot Entry Name | ERLEC_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000068912 |
| Target Classification | N/A |
The target: ERLEC1, gene name: ERLEC1, also named as C2orf30, CIM, CL24936, CL25084, HEL117, XTP3-B, XTP3TPB. This gene encodes a resident endoplasmic reticulum (ER) protein that functions in N-glycan recognition. This protein is thought to be involved in ER-associated degradation via its interaction with the membrane-associated ubiquitin ligase complex. It also functions as a regulator of multiple cellular stress-response pathways in a manner that promotes metastatic cell survival. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 21. [provided by RefSeq, Aug 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
