Anti-NF2L1/ NFE2L1/ LCR-F1 functional antibody

Anti-NF2L1/ NFE2L1/ LCR-F1 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to NFE2L1/NFE2L1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1423-Ab-1/ GM-Tg-hg-SE1423-Ab-2Anti-Human NFE2L1 monoclonal antibodyHuman
GM-Tg-rg-SE1423-Ab-1/ GM-Tg-rg-SE1423-Ab-2Anti-Rat NFE2L1 monoclonal antibodyRat
GM-Tg-mg-SE1423-Ab-1/ GM-Tg-mg-SE1423-Ab-2Anti-Mouse NFE2L1 monoclonal antibodyMouse
GM-Tg-cynog-SE1423-Ab-1/ GM-Tg-cynog-SE1423-Ab-2Anti-Cynomolgus/ Rhesus macaque NFE2L1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1423-Ab-1/ GM-Tg-felg-SE1423-Ab-2Anti-Feline NFE2L1 monoclonal antibodyFeline
GM-Tg-cang-SE1423-Ab-1/ GM-Tg-cang-SE1423-Ab-2Anti-Canine NFE2L1 monoclonal antibodyCanine
GM-Tg-bovg-SE1423-Ab-1/ GM-Tg-bovg-SE1423-Ab-2Anti-Bovine NFE2L1 monoclonal antibodyBovine
GM-Tg-equg-SE1423-Ab-1/ GM-Tg-equg-SE1423-Ab-2Anti-Equine NFE2L1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1423-Ab-1/ GM-Tg-hg-SE1423-Ab-2; GM-Tg-rg-SE1423-Ab-1/ GM-Tg-rg-SE1423-Ab-2;
GM-Tg-mg-SE1423-Ab-1/ GM-Tg-mg-SE1423-Ab-2; GM-Tg-cynog-SE1423-Ab-1/ GM-Tg-cynog-SE1423-Ab-2;
GM-Tg-felg-SE1423-Ab-1/ GM-Tg-felg-SE1423-Ab-2; GM-Tg-cang-SE1423-Ab-1/ GM-Tg-cang-SE1423-Ab-2;
GM-Tg-bovg-SE1423-Ab-1/ GM-Tg-bovg-SE1423-Ab-2; GM-Tg-equg-SE1423-Ab-1/ GM-Tg-equg-SE1423-Ab-2
Products NameAnti-NFE2L1 monoclonal antibody
Formatmab
Target NameNFE2L1
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-NFE2L1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1423-Ag-1Recombinant multi-species NF2L1/ NFE2L1/ LCR-F1 protein
    ORF Viral VectorpGMLPm004418mouse Nfe2l1 Lentivirus plasmid
    ORF Viral VectorvGMLPm004418mouse Nfe2l1 Lentivirus particle


    Target information

    Target IDGM-SE1423
    Target NameNFE2L1
    Gene ID4779,18023,360610,695404,403692,101084497,534582,100069329
    Gene Symbol and SynonymsLCR-F1,Lcrf1,NFE2L1,NRF-1,NRF1,TCF-11,TCF11
    Uniprot AccessionQ14494,A5D7E9
    Uniprot Entry NameNF2L1_HUMAN,NF2L1_BOVIN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000082641
    Target ClassificationN/A

    The target: NFE2L1, gene name: NFE2L1, also named as LCR-F1, NRF1, TCF11. This gene encodes a protein that is involved in globin gene expression in erythrocytes. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene, NFE2L1, and for "nuclear respiratory factor 1" which has an official symbol of NRF1. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.