Anti-SCOT1/ OXCT1/ OXCT functional antibody
Anti-SCOT1/ OXCT1/ OXCT functional antibody for cell culture, ELISA & in-vivo assay
Go to OXCT1/OXCT1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-SE1425-Ab-1/ GM-Tg-hg-SE1425-Ab-2 | Anti-Human OXCT1 monoclonal antibody | Human |
GM-Tg-rg-SE1425-Ab-1/ GM-Tg-rg-SE1425-Ab-2 | Anti-Rat OXCT1 monoclonal antibody | Rat |
GM-Tg-mg-SE1425-Ab-1/ GM-Tg-mg-SE1425-Ab-2 | Anti-Mouse OXCT1 monoclonal antibody | Mouse |
GM-Tg-cynog-SE1425-Ab-1/ GM-Tg-cynog-SE1425-Ab-2 | Anti-Cynomolgus/ Rhesus macaque OXCT1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-SE1425-Ab-1/ GM-Tg-felg-SE1425-Ab-2 | Anti-Feline OXCT1 monoclonal antibody | Feline |
GM-Tg-cang-SE1425-Ab-1/ GM-Tg-cang-SE1425-Ab-2 | Anti-Canine OXCT1 monoclonal antibody | Canine |
GM-Tg-bovg-SE1425-Ab-1/ GM-Tg-bovg-SE1425-Ab-2 | Anti-Bovine OXCT1 monoclonal antibody | Bovine |
GM-Tg-equg-SE1425-Ab-1/ GM-Tg-equg-SE1425-Ab-2 | Anti-Equine OXCT1 monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-SE1425-Ab-1/ GM-Tg-hg-SE1425-Ab-2; GM-Tg-rg-SE1425-Ab-1/ GM-Tg-rg-SE1425-Ab-2; GM-Tg-mg-SE1425-Ab-1/ GM-Tg-mg-SE1425-Ab-2; GM-Tg-cynog-SE1425-Ab-1/ GM-Tg-cynog-SE1425-Ab-2; GM-Tg-felg-SE1425-Ab-1/ GM-Tg-felg-SE1425-Ab-2; GM-Tg-cang-SE1425-Ab-1/ GM-Tg-cang-SE1425-Ab-2; GM-Tg-bovg-SE1425-Ab-1/ GM-Tg-bovg-SE1425-Ab-2; GM-Tg-equg-SE1425-Ab-1/ GM-Tg-equg-SE1425-Ab-2 |
Products Name | Anti-OXCT1 monoclonal antibody |
Format | mab |
Target Name | OXCT1 |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category of antibody | FACS/Biofunctional Antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-OXCT1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | GM-Tg-g-SE1425-Ag-1 | Recombinant multi-species SCOT1/ OXCT1/ OXCT protein |
ORF Viral Vector | pGMLP002300 | human OXCT1 Lentivirus plasmid |
ORF Viral Vector | vGMLP002300 | human OXCT1 Lentivirus particle |
ORF Viral Vector | pGMLPm002757 | mouse Oxct1 Lentivirus plasmid |
ORF Viral Vector | vGMLPm002757 | mouse Oxct1 Lentivirus particle |
Target information
Target ID | GM-SE1425 |
Target Name | OXCT1 |
Gene ID | 5019,67041,690163,696642,479347,100151771,535804,100065846 |
Gene Symbol and Synonyms | 2610008O03Rik,OXCT,OXCT1,Oxct2a,SCOT,Scot-s |
Uniprot Accession | P55809,B2GV06 |
Uniprot Entry Name | SCOT1_HUMAN,SCOT1_RAT |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category | |
Disease | Breast Cancer |
Gene Ensembl | ENSG00000083720 |
Target Classification | N/A |
The target: OXCT1, gene name: OXCT1, also named as OXCT, SCOT. This gene encodes a member of the 3-oxoacid CoA-transferase gene family. The encoded protein is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate. Mutations in this gene are associated with succinyl CoA:3-oxoacid CoA transferase deficiency. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.