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Anti-DDX17/ P72/ RH70 functional antibody
Anti-DDX17/ P72/ RH70 functional antibody for cell culture, ELISA & in-vivo assay
Go to DDX17/DDX17 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1435-Ab-1/ GM-Tg-hg-SE1435-Ab-2 | Anti-Human DDX17 monoclonal antibody | Human |
| GM-Tg-rg-SE1435-Ab-1/ GM-Tg-rg-SE1435-Ab-2 | Anti-Rat DDX17 monoclonal antibody | Rat |
| GM-Tg-mg-SE1435-Ab-1/ GM-Tg-mg-SE1435-Ab-2 | Anti-Mouse DDX17 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1435-Ab-1/ GM-Tg-cynog-SE1435-Ab-2 | Anti-Cynomolgus/ Rhesus macaque DDX17 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1435-Ab-1/ GM-Tg-felg-SE1435-Ab-2 | Anti-Feline DDX17 monoclonal antibody | Feline |
| GM-Tg-cang-SE1435-Ab-1/ GM-Tg-cang-SE1435-Ab-2 | Anti-Canine DDX17 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1435-Ab-1/ GM-Tg-bovg-SE1435-Ab-2 | Anti-Bovine DDX17 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1435-Ab-1/ GM-Tg-equg-SE1435-Ab-2 | Anti-Equine DDX17 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1435-Ab-1/ GM-Tg-hg-SE1435-Ab-2; GM-Tg-rg-SE1435-Ab-1/ GM-Tg-rg-SE1435-Ab-2; GM-Tg-mg-SE1435-Ab-1/ GM-Tg-mg-SE1435-Ab-2; GM-Tg-cynog-SE1435-Ab-1/ GM-Tg-cynog-SE1435-Ab-2; GM-Tg-felg-SE1435-Ab-1/ GM-Tg-felg-SE1435-Ab-2; GM-Tg-cang-SE1435-Ab-1/ GM-Tg-cang-SE1435-Ab-2; GM-Tg-bovg-SE1435-Ab-1/ GM-Tg-bovg-SE1435-Ab-2; GM-Tg-equg-SE1435-Ab-1/ GM-Tg-equg-SE1435-Ab-2 |
| Products Name | Anti-DDX17 monoclonal antibody |
| Format | mab |
| Target Name | DDX17 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-DDX17 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1435-Ag-1 | Recombinant multi-species DDX17/ P72/ RH70 protein |
| ORF Viral Vector | vGMLP002075 | human DDX17 Lentivirus particle |
| ORF Viral Vector | pGMLP002075 | human DDX17 Lentivirus plasmid |
Target information
| Target ID | GM-SE1435 |
| Target Name | DDX17 |
| Gene ID | 10521,67040,315133,574266,474508,101080643,514323,100070063 |
| Gene Symbol and Synonyms | 2610007K22Rik,A430025E01Rik,DDX17,Gm926,P72,RH70 |
| Uniprot Accession | Q92841 |
| Uniprot Entry Name | DDX17_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000100201 |
| Target Classification | N/A |
The target: DDX17, gene name: DDX17, also named as P72, RH70. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and splicesosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an ATPase activated by a variety of RNA species, but not by dsDNA. This protein, and that encoded by DDX5 gene, are more closely related to each other than to any other member of the DEAD box family. This gene can encode multiple isoforms due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) start codon. [provided by RefSeq, Apr 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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