Anti-SDS3/ SUDS3/ SAP45 functional antibody

Anti-SDS3/ SUDS3/ SAP45 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to SUDS3/SUDS3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1461-Ab-1/ GM-Tg-hg-SE1461-Ab-2Anti-Human SUDS3 monoclonal antibodyHuman
GM-Tg-rg-SE1461-Ab-1/ GM-Tg-rg-SE1461-Ab-2Anti-Rat SUDS3 monoclonal antibodyRat
GM-Tg-mg-SE1461-Ab-1/ GM-Tg-mg-SE1461-Ab-2Anti-Mouse SUDS3 monoclonal antibodyMouse
GM-Tg-cynog-SE1461-Ab-1/ GM-Tg-cynog-SE1461-Ab-2Anti-Cynomolgus/ Rhesus macaque SUDS3 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1461-Ab-1/ GM-Tg-felg-SE1461-Ab-2Anti-Feline SUDS3 monoclonal antibodyFeline
GM-Tg-cang-SE1461-Ab-1/ GM-Tg-cang-SE1461-Ab-2Anti-Canine SUDS3 monoclonal antibodyCanine
GM-Tg-bovg-SE1461-Ab-1/ GM-Tg-bovg-SE1461-Ab-2Anti-Bovine SUDS3 monoclonal antibodyBovine
GM-Tg-equg-SE1461-Ab-1/ GM-Tg-equg-SE1461-Ab-2Anti-Equine SUDS3 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1461-Ab-1/ GM-Tg-hg-SE1461-Ab-2; GM-Tg-rg-SE1461-Ab-1/ GM-Tg-rg-SE1461-Ab-2;
GM-Tg-mg-SE1461-Ab-1/ GM-Tg-mg-SE1461-Ab-2; GM-Tg-cynog-SE1461-Ab-1/ GM-Tg-cynog-SE1461-Ab-2;
GM-Tg-felg-SE1461-Ab-1/ GM-Tg-felg-SE1461-Ab-2; GM-Tg-cang-SE1461-Ab-1/ GM-Tg-cang-SE1461-Ab-2;
GM-Tg-bovg-SE1461-Ab-1/ GM-Tg-bovg-SE1461-Ab-2; GM-Tg-equg-SE1461-Ab-1/ GM-Tg-equg-SE1461-Ab-2
Products NameAnti-SUDS3 monoclonal antibody
Formatmab
Target NameSUDS3
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SUDS3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1461-Ag-1Recombinant multi-species SDS3/ SUDS3/ SAP45 protein


    Target information

    Target IDGM-SE1461
    Target NameSUDS3
    Gene ID64426,71954,360819,696166,100856145,101093302,506646,100054578
    Gene Symbol and Synonyms2400003N08Rik,2410008L21Rik,mSds3,RGD1305986,SAP45,SDS3,SUDS3
    Uniprot AccessionQ9H7L9,A6H6W9
    Uniprot Entry NameSDS3_HUMAN,SDS3_BOVIN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000111707
    Target ClassificationN/A

    The target: SUDS3, gene name: SUDS3, also named as SAP45, SDS3. SDS3 is a subunit of the histone deacetylase (see HDAC1; MIM 601241)-dependent SIN3A (MIM 607776) corepressor complex (Fleischer et al., 2003 [PubMed 12724404]).[supplied by OMIM, Mar 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.