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Anti-NU155/ NUP155/ ATFB15 functional antibody
Anti-NU155/ NUP155/ ATFB15 functional antibody for cell culture, ELISA & in-vivo assay
Go to NUP155/NUP155 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1466-Ab-1/ GM-Tg-hg-SE1466-Ab-2 | Anti-Human NUP155 monoclonal antibody | Human |
| GM-Tg-rg-SE1466-Ab-1/ GM-Tg-rg-SE1466-Ab-2 | Anti-Rat NUP155 monoclonal antibody | Rat |
| GM-Tg-mg-SE1466-Ab-1/ GM-Tg-mg-SE1466-Ab-2 | Anti-Mouse NUP155 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1466-Ab-1/ GM-Tg-cynog-SE1466-Ab-2 | Anti-Cynomolgus/ Rhesus macaque NUP155 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1466-Ab-1/ GM-Tg-felg-SE1466-Ab-2 | Anti-Feline NUP155 monoclonal antibody | Feline |
| GM-Tg-cang-SE1466-Ab-1/ GM-Tg-cang-SE1466-Ab-2 | Anti-Canine NUP155 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1466-Ab-1/ GM-Tg-bovg-SE1466-Ab-2 | Anti-Bovine NUP155 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1466-Ab-1/ GM-Tg-equg-SE1466-Ab-2 | Anti-Equine NUP155 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1466-Ab-1/ GM-Tg-hg-SE1466-Ab-2; GM-Tg-rg-SE1466-Ab-1/ GM-Tg-rg-SE1466-Ab-2; GM-Tg-mg-SE1466-Ab-1/ GM-Tg-mg-SE1466-Ab-2; GM-Tg-cynog-SE1466-Ab-1/ GM-Tg-cynog-SE1466-Ab-2; GM-Tg-felg-SE1466-Ab-1/ GM-Tg-felg-SE1466-Ab-2; GM-Tg-cang-SE1466-Ab-1/ GM-Tg-cang-SE1466-Ab-2; GM-Tg-bovg-SE1466-Ab-1/ GM-Tg-bovg-SE1466-Ab-2; GM-Tg-equg-SE1466-Ab-1/ GM-Tg-equg-SE1466-Ab-2 |
| Products Name | Anti-NUP155 monoclonal antibody |
| Format | mab |
| Target Name | NUP155 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-NUP155 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1466-Ag-1 | Recombinant multi-species NU155/ NUP155/ ATFB15 protein |
Target information
| Target ID | GM-SE1466 |
| Target Name | NUP155 |
| Gene ID | 9631,170762,117021,100426110,479360,101096702,506738,100053405 |
| Gene Symbol and Synonyms | ATFB15,D930027M19Rik,mKIAA0791,N155,NUP155 |
| Uniprot Accession | O75694,P37199 |
| Uniprot Entry Name | NU155_HUMAN,NU155_RAT |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000113569 |
| Target Classification | N/A |
The target: NUP155, gene name: NUP155, also named as ATFB15, N155. Nucleoporins are proteins that play an important role in the assembly and functioning of the nuclear pore complex (NPC) which regulates the movement of macromolecules across the nuclear envelope (NE). The protein encoded by this gene plays a role in the fusion of NE vesicles and formation of the double membrane NE. The protein may also be involved in cardiac physiology and may be associated with the pathogenesis of atrial fibrillation. Alternative splicing results in multiple transcript variants of this gene. A pseudogene associated with this gene is located on chromosome 6. [provided by RefSeq, May 2013].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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