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Anti-PCCB functional antibody
Anti-PCCB functional antibody for cell culture, ELISA & in-vivo assay
Go to PCCB/PCCB products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1467-Ab-1/ GM-Tg-hg-SE1467-Ab-2 | Anti-Human PCCB monoclonal antibody | Human |
| GM-Tg-rg-SE1467-Ab-1/ GM-Tg-rg-SE1467-Ab-2 | Anti-Rat PCCB monoclonal antibody | Rat |
| GM-Tg-mg-SE1467-Ab-1/ GM-Tg-mg-SE1467-Ab-2 | Anti-Mouse PCCB monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1467-Ab-1/ GM-Tg-cynog-SE1467-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PCCB monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1467-Ab-1/ GM-Tg-felg-SE1467-Ab-2 | Anti-Feline PCCB monoclonal antibody | Feline |
| GM-Tg-cang-SE1467-Ab-1/ GM-Tg-cang-SE1467-Ab-2 | Anti-Canine PCCB monoclonal antibody | Canine |
| GM-Tg-bovg-SE1467-Ab-1/ GM-Tg-bovg-SE1467-Ab-2 | Anti-Bovine PCCB monoclonal antibody | Bovine |
| GM-Tg-equg-SE1467-Ab-1/ GM-Tg-equg-SE1467-Ab-2 | Anti-Equine PCCB monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1467-Ab-1/ GM-Tg-hg-SE1467-Ab-2; GM-Tg-rg-SE1467-Ab-1/ GM-Tg-rg-SE1467-Ab-2; GM-Tg-mg-SE1467-Ab-1/ GM-Tg-mg-SE1467-Ab-2; GM-Tg-cynog-SE1467-Ab-1/ GM-Tg-cynog-SE1467-Ab-2; GM-Tg-felg-SE1467-Ab-1/ GM-Tg-felg-SE1467-Ab-2; GM-Tg-cang-SE1467-Ab-1/ GM-Tg-cang-SE1467-Ab-2; GM-Tg-bovg-SE1467-Ab-1/ GM-Tg-bovg-SE1467-Ab-2; GM-Tg-equg-SE1467-Ab-1/ GM-Tg-equg-SE1467-Ab-2 |
| Products Name | Anti-PCCB monoclonal antibody |
| Format | mab |
| Target Name | PCCB |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-PCCB benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1467-Ag-1 | Recombinant multi-species PCCB protein |
| ORF Viral Vector | vGMLP002156 | human PCCB Lentivirus particle |
| ORF Viral Vector | pGMLP002156 | human PCCB Lentivirus plasmid |
| ORF Viral Vector | pGMLPm002749 | mouse Pccb Lentivirus plasmid |
| ORF Viral Vector | vGMLPm002749 | mouse Pccb Lentivirus particle |
Target information
| Target ID | GM-SE1467 |
| Target Name | PCCB |
| Gene ID | 5096,66904,24624,716964,477076,101082847,515902,100065950 |
| Gene Symbol and Synonyms | 1300012P06Rik,PCCB |
| Uniprot Accession | P05166,P07633,Q2TBR0 |
| Uniprot Entry Name | PCCB_HUMAN,PCCB_RAT,PCCB_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000114054 |
| Target Classification | N/A |
The target: PCCB, gene name: PCCB, also named as . The protein encoded by this gene is a subunit of the propionyl-CoA carboxylase (PCC) enzyme, which is involved in the catabolism of propionyl-CoA. PCC is a mitochondrial enzyme that probably acts as a dodecamer of six alpha subunits and six beta subunits. This gene encodes the beta subunit of PCC. Defects in this gene are a cause of propionic acidemia type II (PA-2). Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
