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Anti-MTX2 functional antibody
Anti-MTX2 functional antibody for cell culture, ELISA & in-vivo assay
Go to MTX2/MTX2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1490-Ab-1/ GM-Tg-hg-SE1490-Ab-2 | Anti-Human MTX2 monoclonal antibody | Human |
| GM-Tg-rg-SE1490-Ab-1/ GM-Tg-rg-SE1490-Ab-2 | Anti-Rat MTX2 monoclonal antibody | Rat |
| GM-Tg-mg-SE1490-Ab-1/ GM-Tg-mg-SE1490-Ab-2 | Anti-Mouse MTX2 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1490-Ab-1/ GM-Tg-cynog-SE1490-Ab-2 | Anti-Cynomolgus/ Rhesus macaque MTX2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1490-Ab-1/ GM-Tg-felg-SE1490-Ab-2 | Anti-Feline MTX2 monoclonal antibody | Feline |
| GM-Tg-cang-SE1490-Ab-1/ GM-Tg-cang-SE1490-Ab-2 | Anti-Canine MTX2 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1490-Ab-1/ GM-Tg-bovg-SE1490-Ab-2 | Anti-Bovine MTX2 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1490-Ab-1/ GM-Tg-equg-SE1490-Ab-2 | Anti-Equine MTX2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1490-Ab-1/ GM-Tg-hg-SE1490-Ab-2; GM-Tg-rg-SE1490-Ab-1/ GM-Tg-rg-SE1490-Ab-2; GM-Tg-mg-SE1490-Ab-1/ GM-Tg-mg-SE1490-Ab-2; GM-Tg-cynog-SE1490-Ab-1/ GM-Tg-cynog-SE1490-Ab-2; GM-Tg-felg-SE1490-Ab-1/ GM-Tg-felg-SE1490-Ab-2; GM-Tg-cang-SE1490-Ab-1/ GM-Tg-cang-SE1490-Ab-2; GM-Tg-bovg-SE1490-Ab-1/ GM-Tg-bovg-SE1490-Ab-2; GM-Tg-equg-SE1490-Ab-1/ GM-Tg-equg-SE1490-Ab-2 |
| Products Name | Anti-MTX2 monoclonal antibody |
| Format | mab |
| Target Name | MTX2 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-MTX2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1490-Ag-1 | Recombinant multi-species MTX2 protein |
Target information
| Target ID | GM-SE1490 |
| Target Name | MTX2 |
| Gene ID | 10651,53375,288150,701294,478811,101093629,615424,100066490 |
| Gene Symbol and Synonyms | 1500012G02Rik,MDPS,metaxin-2,MTX2 |
| Uniprot Accession | O75431 |
| Uniprot Entry Name | MTX2_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000128654 |
| Target Classification | N/A |
The target: MTX2, gene name: MTX2, also named as . The protein encoded by this gene is highly similar to the metaxin 2 protein from mouse, which has been shown to interact with the mitochondrial membrane protein metaxin 1. Because of this similarity, it is thought that the encoded protein is peripherally associated with the cytosolic face of the outer mitochondrial membrane, and that it is involved in the import of proteins into the mitochondrion. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Jun 2009].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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