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Anti-NDUAA/ NDUFA10/ CI-42KD functional antibody
Anti-NDUAA/ NDUFA10/ CI-42KD functional antibody for cell culture, ELISA & in-vivo assay
Go to NDUFA10/NDUFA10 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1493-Ab-1/ GM-Tg-hg-SE1493-Ab-2 | Anti-Human NDUFA10 monoclonal antibody | Human |
| GM-Tg-rg-SE1493-Ab-1/ GM-Tg-rg-SE1493-Ab-2 | Anti-Rat NDUFA10 monoclonal antibody | Rat |
| GM-Tg-mg-SE1493-Ab-1/ GM-Tg-mg-SE1493-Ab-2 | Anti-Mouse NDUFA10 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1493-Ab-1/ GM-Tg-cynog-SE1493-Ab-2 | Anti-Cynomolgus/ Rhesus macaque NDUFA10 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1493-Ab-1/ GM-Tg-felg-SE1493-Ab-2 | Anti-Feline NDUFA10 monoclonal antibody | Feline |
| GM-Tg-cang-SE1493-Ab-1/ GM-Tg-cang-SE1493-Ab-2 | Anti-Canine NDUFA10 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1493-Ab-1/ GM-Tg-bovg-SE1493-Ab-2 | Anti-Bovine NDUFA10 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1493-Ab-1/ GM-Tg-equg-SE1493-Ab-2 | Anti-Equine NDUFA10 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1493-Ab-1/ GM-Tg-hg-SE1493-Ab-2; GM-Tg-rg-SE1493-Ab-1/ GM-Tg-rg-SE1493-Ab-2; GM-Tg-mg-SE1493-Ab-1/ GM-Tg-mg-SE1493-Ab-2; GM-Tg-cynog-SE1493-Ab-1/ GM-Tg-cynog-SE1493-Ab-2; GM-Tg-felg-SE1493-Ab-1/ GM-Tg-felg-SE1493-Ab-2; GM-Tg-cang-SE1493-Ab-1/ GM-Tg-cang-SE1493-Ab-2; GM-Tg-bovg-SE1493-Ab-1/ GM-Tg-bovg-SE1493-Ab-2; GM-Tg-equg-SE1493-Ab-1/ GM-Tg-equg-SE1493-Ab-2 |
| Products Name | Anti-NDUFA10 monoclonal antibody |
| Format | mab |
| Target Name | NDUFA10 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-NDUFA10 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1493-Ag-1 | Recombinant multi-species NDUAA/ NDUFA10/ CI-42KD protein |
Target information
| Target ID | GM-SE1493 |
| Target Name | NDUFA10 |
| Gene ID | 4705,67273,678759,697681,608244,101093631,338060,100057698 |
| Gene Symbol and Synonyms | 2900053E13Rik,CI-42k,CI-42KD,MC1DN22,NDUFA10,ndufa10l |
| Uniprot Accession | O95299,Q561S0,P54713,P34942 |
| Uniprot Entry Name | NDUAA_HUMAN,NDUAA_RAT,NDUAA_CANLF,NDUAA_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | Breast Cancer |
| Gene Ensembl | ENSG00000130414 |
| Target Classification | N/A |
The target: NDUFA10, gene name: NDUFA10, also named as CI-42KD, CI-42k. The protein encoded by this gene is a component of 42 kDa complex I, the first enzyme complex in the electron transport chain of mitochondria. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. A mutation in this gene was found in an individual with Leigh syndrome. [provided by RefSeq, Apr 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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