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Anti-RDH5/ 9cRDH/ HSD17B9 functional antibody
Anti-RDH5/ 9cRDH/ HSD17B9 functional antibody for cell culture, ELISA & in-vivo assay
Go to RDH5/RDH5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1504-Ab-1/ GM-Tg-hg-SE1504-Ab-2 | Anti-Human RDH5 monoclonal antibody | Human |
| GM-Tg-rg-SE1504-Ab-1/ GM-Tg-rg-SE1504-Ab-2 | Anti-Rat RDH5 monoclonal antibody | Rat |
| GM-Tg-mg-SE1504-Ab-1/ GM-Tg-mg-SE1504-Ab-2 | Anti-Mouse RDH5 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1504-Ab-1/ GM-Tg-cynog-SE1504-Ab-2 | Anti-Cynomolgus/ Rhesus macaque RDH5 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1504-Ab-1/ GM-Tg-felg-SE1504-Ab-2 | Anti-Feline RDH5 monoclonal antibody | Feline |
| GM-Tg-cang-SE1504-Ab-1/ GM-Tg-cang-SE1504-Ab-2 | Anti-Canine RDH5 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1504-Ab-1/ GM-Tg-bovg-SE1504-Ab-2 | Anti-Bovine RDH5 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1504-Ab-1/ GM-Tg-equg-SE1504-Ab-2 | Anti-Equine RDH5 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1504-Ab-1/ GM-Tg-hg-SE1504-Ab-2; GM-Tg-rg-SE1504-Ab-1/ GM-Tg-rg-SE1504-Ab-2; GM-Tg-mg-SE1504-Ab-1/ GM-Tg-mg-SE1504-Ab-2; GM-Tg-cynog-SE1504-Ab-1/ GM-Tg-cynog-SE1504-Ab-2; GM-Tg-felg-SE1504-Ab-1/ GM-Tg-felg-SE1504-Ab-2; GM-Tg-cang-SE1504-Ab-1/ GM-Tg-cang-SE1504-Ab-2; GM-Tg-bovg-SE1504-Ab-1/ GM-Tg-bovg-SE1504-Ab-2; GM-Tg-equg-SE1504-Ab-1/ GM-Tg-equg-SE1504-Ab-2 |
| Products Name | Anti-RDH5 monoclonal antibody |
| Format | mab |
| Target Name | RDH5 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-RDH5 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1504-Ag-1 | Recombinant multi-species RDH5/ 9cRDH/ HSD17B9 protein |
| ORF Viral Vector | pGMLP004058 | human RDH5 Lentivirus plasmid |
| ORF Viral Vector | vGMLP004058 | human RDH5 Lentivirus particle |
| ORF Viral Vector | pGMLPm000434 | mouse Rdh5 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000434 | mouse Rdh5 Lentivirus particle |
Target information
| Target ID | GM-SE1504 |
| Target Name | RDH5 |
| Gene ID | 5959,19682,366791,709644,481098,101090450,281448,100051379 |
| Gene Symbol and Synonyms | 9-cis,9cRDH,cRDH,HSD17B9,P32,RDH1,RDH4,RDH5,SDR9C5 |
| Uniprot Accession | Q92781,Q27979 |
| Uniprot Entry Name | RDH5_HUMAN,RDH5_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000135437 |
| Target Classification | N/A |
The target: RDH5, gene name: RDH5, also named as 9cRDH, HSD17B9, RDH1, SDR9C5. This gene encodes an enzyme belonging to the short-chain dehydrogenases/reductases (SDR) family. This retinol dehydrogenase functions to catalyze the final step in the biosynthesis of 11-cis retinaldehyde, which is the universal chromophore of visual pigments. Mutations in this gene cause autosomal recessive fundus albipunctatus, a rare form of night blindness that is characterized by a delay in the regeneration of cone and rod photopigments. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S1 (biogenesis of lysosomal organelles complex-1, subunit 1) gene. [provided by RefSeq, Dec 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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