Anti-ERP27/ C12orf46/ PDIA8 functional antibody

Anti-ERP27/ C12orf46/ PDIA8 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to ERP27/ERP27 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1509-Ab-1/ GM-Tg-hg-SE1509-Ab-2Anti-Human ERP27 monoclonal antibodyHuman
GM-Tg-rg-SE1509-Ab-1/ GM-Tg-rg-SE1509-Ab-2Anti-Rat ERP27 monoclonal antibodyRat
GM-Tg-mg-SE1509-Ab-1/ GM-Tg-mg-SE1509-Ab-2Anti-Mouse ERP27 monoclonal antibodyMouse
GM-Tg-cynog-SE1509-Ab-1/ GM-Tg-cynog-SE1509-Ab-2Anti-Cynomolgus/ Rhesus macaque ERP27 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1509-Ab-1/ GM-Tg-felg-SE1509-Ab-2Anti-Feline ERP27 monoclonal antibodyFeline
GM-Tg-cang-SE1509-Ab-1/ GM-Tg-cang-SE1509-Ab-2Anti-Canine ERP27 monoclonal antibodyCanine
GM-Tg-bovg-SE1509-Ab-1/ GM-Tg-bovg-SE1509-Ab-2Anti-Bovine ERP27 monoclonal antibodyBovine
GM-Tg-equg-SE1509-Ab-1/ GM-Tg-equg-SE1509-Ab-2Anti-Equine ERP27 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1509-Ab-1/ GM-Tg-hg-SE1509-Ab-2; GM-Tg-rg-SE1509-Ab-1/ GM-Tg-rg-SE1509-Ab-2;
GM-Tg-mg-SE1509-Ab-1/ GM-Tg-mg-SE1509-Ab-2; GM-Tg-cynog-SE1509-Ab-1/ GM-Tg-cynog-SE1509-Ab-2;
GM-Tg-felg-SE1509-Ab-1/ GM-Tg-felg-SE1509-Ab-2; GM-Tg-cang-SE1509-Ab-1/ GM-Tg-cang-SE1509-Ab-2;
GM-Tg-bovg-SE1509-Ab-1/ GM-Tg-bovg-SE1509-Ab-2; GM-Tg-equg-SE1509-Ab-1/ GM-Tg-equg-SE1509-Ab-2
Products NameAnti-ERP27 monoclonal antibody
Formatmab
Target NameERP27
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-ERP27 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1509-Ag-1Recombinant multi-species ERP27/ C12orf46/ PDIA8 protein


    Target information

    Target IDGM-SE1509
    Target NameERP27
    Gene ID121506,69187,297698,700186,486667,101096994,505855,100063970
    Gene Symbol and Synonyms1810033M07Rik,1810047B09Rik,C12orf46,ERP27,PDIA8,RGD1565381
    Uniprot AccessionQ96DN0,Q32L47
    Uniprot Entry NameERP27_HUMAN,ERP27_BOVIN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000139055
    Target ClassificationN/A

    The target: ERP27, gene name: ERP27, also named as C12orf46, PDIA8. This gene encodes a noncatalytic member of the protein disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins. The canonical protein has an N-terminal signal sequence, two thioredoxin (TRX)-like domains and a C-terminal ER-retention sequence. Alternative splicing results in multiple transcript variants encoding distinct isoforms; some of which lack domains present in the canonical protein. [provided by RefSeq, Dec 2016].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.