Anti-CSAD/ CSD/ PCAP functional antibody

Anti-CSAD/ CSD/ PCAP functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to CSAD/CSAD products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1511-Ab-1/ GM-Tg-hg-SE1511-Ab-2Anti-Human CSAD monoclonal antibodyHuman
GM-Tg-rg-SE1511-Ab-1/ GM-Tg-rg-SE1511-Ab-2Anti-Rat CSAD monoclonal antibodyRat
GM-Tg-mg-SE1511-Ab-1/ GM-Tg-mg-SE1511-Ab-2Anti-Mouse CSAD monoclonal antibodyMouse
GM-Tg-cynog-SE1511-Ab-1/ GM-Tg-cynog-SE1511-Ab-2Anti-Cynomolgus/ Rhesus macaque CSAD monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1511-Ab-1/ GM-Tg-felg-SE1511-Ab-2Anti-Feline CSAD monoclonal antibodyFeline
GM-Tg-cang-SE1511-Ab-1/ GM-Tg-cang-SE1511-Ab-2Anti-Canine CSAD monoclonal antibodyCanine
GM-Tg-bovg-SE1511-Ab-1/ GM-Tg-bovg-SE1511-Ab-2Anti-Bovine CSAD monoclonal antibodyBovine
GM-Tg-equg-SE1511-Ab-1/ GM-Tg-equg-SE1511-Ab-2Anti-Equine CSAD monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1511-Ab-1/ GM-Tg-hg-SE1511-Ab-2; GM-Tg-rg-SE1511-Ab-1/ GM-Tg-rg-SE1511-Ab-2;
GM-Tg-mg-SE1511-Ab-1/ GM-Tg-mg-SE1511-Ab-2; GM-Tg-cynog-SE1511-Ab-1/ GM-Tg-cynog-SE1511-Ab-2;
GM-Tg-felg-SE1511-Ab-1/ GM-Tg-felg-SE1511-Ab-2; GM-Tg-cang-SE1511-Ab-1/ GM-Tg-cang-SE1511-Ab-2;
GM-Tg-bovg-SE1511-Ab-1/ GM-Tg-bovg-SE1511-Ab-2; GM-Tg-equg-SE1511-Ab-1/ GM-Tg-equg-SE1511-Ab-2
Products NameAnti-CSAD monoclonal antibody
Formatmab
Target NameCSAD
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CSAD benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1511-Ag-1Recombinant multi-species CSAD/ CSD/ PCAP protein


    Target information

    Target IDGM-SE1511
    Target NameCSAD
    Gene ID51380,246277,60356,701290,486510,101099732,516241,100061989
    Gene Symbol and SynonymsCSAD,CSD,PCAP
    Uniprot AccessionQ9Y600,Q64611
    Uniprot Entry NameCSAD_HUMAN,CSAD_RAT
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000139631
    Target ClassificationN/A

    The target: CSAD, gene name: CSAD, also named as CSD, PCAP. This gene encodes a member of the group 2 decarboxylase family. A similar protein in rodents plays a role in multiple biological processes as the rate-limiting enzyme in taurine biosynthesis, catalyzing the decarboxylation of cysteinesulfinate to hypotaurine. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.