Anti-RCAS1/ EBAG9/ EB9 functional antibody
Anti-RCAS1/ EBAG9/ EB9 functional antibody for cell culture, ELISA & in-vivo assay
Go to EBAG9/EBAG9 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-SE1532-Ab-1/ GM-Tg-hg-SE1532-Ab-2 | Anti-Human EBAG9 monoclonal antibody | Human |
GM-Tg-rg-SE1532-Ab-1/ GM-Tg-rg-SE1532-Ab-2 | Anti-Rat EBAG9 monoclonal antibody | Rat |
GM-Tg-mg-SE1532-Ab-1/ GM-Tg-mg-SE1532-Ab-2 | Anti-Mouse EBAG9 monoclonal antibody | Mouse |
GM-Tg-cynog-SE1532-Ab-1/ GM-Tg-cynog-SE1532-Ab-2 | Anti-Cynomolgus/ Rhesus macaque EBAG9 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-SE1532-Ab-1/ GM-Tg-felg-SE1532-Ab-2 | Anti-Feline EBAG9 monoclonal antibody | Feline |
GM-Tg-cang-SE1532-Ab-1/ GM-Tg-cang-SE1532-Ab-2 | Anti-Canine EBAG9 monoclonal antibody | Canine |
GM-Tg-bovg-SE1532-Ab-1/ GM-Tg-bovg-SE1532-Ab-2 | Anti-Bovine EBAG9 monoclonal antibody | Bovine |
GM-Tg-equg-SE1532-Ab-1/ GM-Tg-equg-SE1532-Ab-2 | Anti-Equine EBAG9 monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-SE1532-Ab-1/ GM-Tg-hg-SE1532-Ab-2; GM-Tg-rg-SE1532-Ab-1/ GM-Tg-rg-SE1532-Ab-2; GM-Tg-mg-SE1532-Ab-1/ GM-Tg-mg-SE1532-Ab-2; GM-Tg-cynog-SE1532-Ab-1/ GM-Tg-cynog-SE1532-Ab-2; GM-Tg-felg-SE1532-Ab-1/ GM-Tg-felg-SE1532-Ab-2; GM-Tg-cang-SE1532-Ab-1/ GM-Tg-cang-SE1532-Ab-2; GM-Tg-bovg-SE1532-Ab-1/ GM-Tg-bovg-SE1532-Ab-2; GM-Tg-equg-SE1532-Ab-1/ GM-Tg-equg-SE1532-Ab-2 |
Products Name | Anti-EBAG9 monoclonal antibody |
Format | mab |
Target Name | EBAG9 |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category of antibody | FACS/Biofunctional Antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-EBAG9 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | GM-Tg-g-SE1532-Ag-1 | Recombinant multi-species RCAS1/ EBAG9/ EB9 protein |
Target information
Target ID | GM-SE1532 |
Target Name | EBAG9 |
Gene ID | 9166,55960,299864,699305,403500,101090232,538551,100064267 |
Gene Symbol and Synonyms | EB9,EBAG9,PDAF,Rcas1 |
Uniprot Accession | O00559,Q5PQP2,Q865S0 |
Uniprot Entry Name | RCAS1_HUMAN,RCAS1_RAT,RCAS1_CANLF |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category | |
Disease | N/A |
Gene Ensembl | ENSG00000147654 |
Target Classification | N/A |
The target: EBAG9, gene name: EBAG9, also named as EB9, PDAF. This gene was identified as an estrogen-responsive gene. Regulation of transcription by estrogen is mediated by estrogen receptor, which binds to the estrogen-responsive element found in the 5'-flanking region of this gene. The encoded protein is a tumor-associated antigen that is expressed at high frequency in a variety of cancers. Alternate splicing results in multiple transcript variants. A pseudogene of this gene has been defined on chromosome 10. [provided by RefSeq, Jul 2013].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.