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Anti-P4HA3 functional antibody
Anti-P4HA3 functional antibody for cell culture, ELISA & in-vivo assay
Go to P4HA3/P4HA3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1538-Ab-1/ GM-Tg-hg-SE1538-Ab-2 | Anti-Human P4HA3 monoclonal antibody | Human |
| GM-Tg-rg-SE1538-Ab-1/ GM-Tg-rg-SE1538-Ab-2 | Anti-Rat P4HA3 monoclonal antibody | Rat |
| GM-Tg-mg-SE1538-Ab-1/ GM-Tg-mg-SE1538-Ab-2 | Anti-Mouse P4HA3 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1538-Ab-1/ GM-Tg-cynog-SE1538-Ab-2 | Anti-Cynomolgus/ Rhesus macaque P4HA3 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1538-Ab-1/ GM-Tg-felg-SE1538-Ab-2 | Anti-Feline P4HA3 monoclonal antibody | Feline |
| GM-Tg-cang-SE1538-Ab-1/ GM-Tg-cang-SE1538-Ab-2 | Anti-Canine P4HA3 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1538-Ab-1/ GM-Tg-bovg-SE1538-Ab-2 | Anti-Bovine P4HA3 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1538-Ab-1/ GM-Tg-equg-SE1538-Ab-2 | Anti-Equine P4HA3 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1538-Ab-1/ GM-Tg-hg-SE1538-Ab-2; GM-Tg-rg-SE1538-Ab-1/ GM-Tg-rg-SE1538-Ab-2; GM-Tg-mg-SE1538-Ab-1/ GM-Tg-mg-SE1538-Ab-2; GM-Tg-cynog-SE1538-Ab-1/ GM-Tg-cynog-SE1538-Ab-2; GM-Tg-felg-SE1538-Ab-1/ GM-Tg-felg-SE1538-Ab-2; GM-Tg-cang-SE1538-Ab-1/ GM-Tg-cang-SE1538-Ab-2; GM-Tg-bovg-SE1538-Ab-1/ GM-Tg-bovg-SE1538-Ab-2; GM-Tg-equg-SE1538-Ab-1/ GM-Tg-equg-SE1538-Ab-2 |
| Products Name | Anti-P4HA3 monoclonal antibody |
| Format | mab |
| Target Name | P4HA3 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-P4HA3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1538-Ag-1 | Recombinant multi-species P4HA3 protein |
Target information
| Target ID | GM-SE1538 |
| Target Name | P4HA3 |
| Gene ID | 283208,320452,361612,718872,609381,101081160,414348,100065260 |
| Gene Symbol and Synonyms | D930031A02Rik,P4HA3 |
| Uniprot Accession | Q7Z4N8,Q6W3E9,Q75UG4 |
| Uniprot Entry Name | P4HA3_HUMAN,P4HA3_RAT,P4HA3_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000149380 |
| Target Classification | N/A |
The target: P4HA3, gene name: P4HA3, also named as . This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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