Anti-MIC27/ APOOL/ CXorf33 functional antibody

Anti-MIC27/ APOOL/ CXorf33 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to APOOL/APOOL products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1541-Ab-1/ GM-Tg-hg-SE1541-Ab-2Anti-Human APOOL monoclonal antibodyHuman
GM-Tg-rg-SE1541-Ab-1/ GM-Tg-rg-SE1541-Ab-2Anti-Rat APOOL monoclonal antibodyRat
GM-Tg-mg-SE1541-Ab-1/ GM-Tg-mg-SE1541-Ab-2Anti-Mouse APOOL monoclonal antibodyMouse
GM-Tg-cynog-SE1541-Ab-1/ GM-Tg-cynog-SE1541-Ab-2Anti-Cynomolgus/ Rhesus macaque APOOL monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1541-Ab-1/ GM-Tg-felg-SE1541-Ab-2Anti-Feline APOOL monoclonal antibodyFeline
GM-Tg-cang-SE1541-Ab-1/ GM-Tg-cang-SE1541-Ab-2Anti-Canine APOOL monoclonal antibodyCanine
GM-Tg-bovg-SE1541-Ab-1/ GM-Tg-bovg-SE1541-Ab-2Anti-Bovine APOOL monoclonal antibodyBovine
GM-Tg-equg-SE1541-Ab-1/ GM-Tg-equg-SE1541-Ab-2Anti-Equine APOOL monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1541-Ab-1/ GM-Tg-hg-SE1541-Ab-2; GM-Tg-rg-SE1541-Ab-1/ GM-Tg-rg-SE1541-Ab-2;
GM-Tg-mg-SE1541-Ab-1/ GM-Tg-mg-SE1541-Ab-2; GM-Tg-cynog-SE1541-Ab-1/ GM-Tg-cynog-SE1541-Ab-2;
GM-Tg-felg-SE1541-Ab-1/ GM-Tg-felg-SE1541-Ab-2; GM-Tg-cang-SE1541-Ab-1/ GM-Tg-cang-SE1541-Ab-2;
GM-Tg-bovg-SE1541-Ab-1/ GM-Tg-bovg-SE1541-Ab-2; GM-Tg-equg-SE1541-Ab-1/ GM-Tg-equg-SE1541-Ab-2
Products NameAnti-APOOL monoclonal antibody
Formatmab
Target NameAPOOL
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-APOOL benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1541-Ag-1Recombinant multi-species MIC27/ APOOL/ CXorf33 protein


    Target information

    Target IDGM-SE1541
    Target NameAPOOL
    Gene ID139322,68117,317191,693763,608758,101098040,506138,100072334
    Gene Symbol and Synonyms6720473G16Rik,9430083G14Rik,APOL,APOOL,CXorf33,E130106L15Rik,FAM121A,Mic27,MICOS27,RGD1549725,UNQ8193
    Uniprot AccessionQ6UXV4,Q3SZ27
    Uniprot Entry NameMIC27_HUMAN,MIC27_BOVIN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000155008
    Target ClassificationN/A

    The target: APOOL, gene name: APOOL, also named as CXorf33, FAM121A, Mic27, UNQ8193. This gene encodes a protein which contains an apolipoprotein O superfamily domain. This domain is found on proteins in circulating lipoprotein complexes. [provided by RefSeq, Sep 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.