Anti-TET5B/ TENT5B/ FAM46B functional antibody

Anti-TET5B/ TENT5B/ FAM46B functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to TENT5B/TENT5B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1546-Ab-1/ GM-Tg-hg-SE1546-Ab-2Anti-Human TENT5B monoclonal antibodyHuman
GM-Tg-rg-SE1546-Ab-1/ GM-Tg-rg-SE1546-Ab-2Anti-Rat TENT5B monoclonal antibodyRat
GM-Tg-mg-SE1546-Ab-1/ GM-Tg-mg-SE1546-Ab-2Anti-Mouse TENT5B monoclonal antibodyMouse
GM-Tg-cynog-SE1546-Ab-1/ GM-Tg-cynog-SE1546-Ab-2Anti-Cynomolgus/ Rhesus macaque TENT5B monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1546-Ab-1/ GM-Tg-felg-SE1546-Ab-2Anti-Feline TENT5B monoclonal antibodyFeline
GM-Tg-cang-SE1546-Ab-1/ GM-Tg-cang-SE1546-Ab-2Anti-Canine TENT5B monoclonal antibodyCanine
GM-Tg-bovg-SE1546-Ab-1/ GM-Tg-bovg-SE1546-Ab-2Anti-Bovine TENT5B monoclonal antibodyBovine
GM-Tg-equg-SE1546-Ab-1/ GM-Tg-equg-SE1546-Ab-2Anti-Equine TENT5B monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1546-Ab-1/ GM-Tg-hg-SE1546-Ab-2; GM-Tg-rg-SE1546-Ab-1/ GM-Tg-rg-SE1546-Ab-2;
GM-Tg-mg-SE1546-Ab-1/ GM-Tg-mg-SE1546-Ab-2; GM-Tg-cynog-SE1546-Ab-1/ GM-Tg-cynog-SE1546-Ab-2;
GM-Tg-felg-SE1546-Ab-1/ GM-Tg-felg-SE1546-Ab-2; GM-Tg-cang-SE1546-Ab-1/ GM-Tg-cang-SE1546-Ab-2;
GM-Tg-bovg-SE1546-Ab-1/ GM-Tg-bovg-SE1546-Ab-2; GM-Tg-equg-SE1546-Ab-1/ GM-Tg-equg-SE1546-Ab-2
Products NameAnti-TENT5B monoclonal antibody
Formatmab
Target NameTENT5B
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-TENT5B benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1546-Ag-1Recombinant multi-species TET5B/ TENT5B/ FAM46B protein


    Target information

    Target IDGM-SE1546
    Target NameTENT5B
    Gene ID115572,100342,313019,715455,119881396,101088503,506745,100070967
    Gene Symbol and Synonyms4732473B16Rik,FAM46,FAM46B,LOC119881396,RGD1308967,TENT5B
    Uniprot AccessionQ96A09,B0BNK8,Q29RH2
    Uniprot Entry NameTET5B_HUMAN,TET5B_RAT,TET5B_BOVIN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000158246
    Target ClassificationN/A

    The target: TENT5B, gene name: TENT5B, also named as FAM46B. Predicted to enable RNA adenylyltransferase activity. Predicted to be involved in mRNA stabilization. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.