Anti-JMJD8/ C16orf20/ PP14397 functional antibody

Anti-JMJD8/ C16orf20/ PP14397 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to JMJD8/JMJD8 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1553-Ab-1/ GM-Tg-hg-SE1553-Ab-2Anti-Human JMJD8 monoclonal antibodyHuman
GM-Tg-rg-SE1553-Ab-1/ GM-Tg-rg-SE1553-Ab-2Anti-Rat JMJD8 monoclonal antibodyRat
GM-Tg-mg-SE1553-Ab-1/ GM-Tg-mg-SE1553-Ab-2Anti-Mouse JMJD8 monoclonal antibodyMouse
GM-Tg-cynog-SE1553-Ab-1/ GM-Tg-cynog-SE1553-Ab-2Anti-Cynomolgus/ Rhesus macaque JMJD8 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1553-Ab-1/ GM-Tg-felg-SE1553-Ab-2Anti-Feline JMJD8 monoclonal antibodyFeline
GM-Tg-cang-SE1553-Ab-1/ GM-Tg-cang-SE1553-Ab-2Anti-Canine JMJD8 monoclonal antibodyCanine
GM-Tg-bovg-SE1553-Ab-1/ GM-Tg-bovg-SE1553-Ab-2Anti-Bovine JMJD8 monoclonal antibodyBovine
GM-Tg-equg-SE1553-Ab-1/ GM-Tg-equg-SE1553-Ab-2Anti-Equine JMJD8 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1553-Ab-1/ GM-Tg-hg-SE1553-Ab-2; GM-Tg-rg-SE1553-Ab-1/ GM-Tg-rg-SE1553-Ab-2;
GM-Tg-mg-SE1553-Ab-1/ GM-Tg-mg-SE1553-Ab-2; GM-Tg-cynog-SE1553-Ab-1/ GM-Tg-cynog-SE1553-Ab-2;
GM-Tg-felg-SE1553-Ab-1/ GM-Tg-felg-SE1553-Ab-2; GM-Tg-cang-SE1553-Ab-1/ GM-Tg-cang-SE1553-Ab-2;
GM-Tg-bovg-SE1553-Ab-1/ GM-Tg-bovg-SE1553-Ab-2; GM-Tg-equg-SE1553-Ab-1/ GM-Tg-equg-SE1553-Ab-2
Products NameAnti-JMJD8 monoclonal antibody
Formatmab
Target NameJMJD8
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-JMJD8 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1553-Ag-1Recombinant multi-species JMJD8/ C16orf20/ PP14397 protein


    Target information

    Target IDGM-SE1553
    Target NameJMJD8
    Gene ID339123,72106,360498,697226,490091,101092574,100139040,100147047
    Gene Symbol and Synonyms2610003J06Rik,C16orf20,JMJD8,PP14397,RGD1307381
    Uniprot AccessionQ96S16,Q6AY40
    Uniprot Entry NameJMJD8_HUMAN,JMJD8_RAT
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000161999
    Target ClassificationN/A

    The target: JMJD8, gene name: JMJD8, also named as C16orf20, PP14397. Involved in several processes, including positive regulation of I-kappaB kinase/NF-kappaB signaling; positive regulation of sprouting angiogenesis; and regulation of glycolytic process. Located in endoplasmic reticulum lumen and nucleus. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.