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Anti-JMJD8/ C16orf20/ PP14397 functional antibody
Anti-JMJD8/ C16orf20/ PP14397 functional antibody for cell culture, ELISA & in-vivo assay
Go to JMJD8/JMJD8 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1553-Ab-1/ GM-Tg-hg-SE1553-Ab-2 | Anti-Human JMJD8 monoclonal antibody | Human |
| GM-Tg-rg-SE1553-Ab-1/ GM-Tg-rg-SE1553-Ab-2 | Anti-Rat JMJD8 monoclonal antibody | Rat |
| GM-Tg-mg-SE1553-Ab-1/ GM-Tg-mg-SE1553-Ab-2 | Anti-Mouse JMJD8 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1553-Ab-1/ GM-Tg-cynog-SE1553-Ab-2 | Anti-Cynomolgus/ Rhesus macaque JMJD8 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1553-Ab-1/ GM-Tg-felg-SE1553-Ab-2 | Anti-Feline JMJD8 monoclonal antibody | Feline |
| GM-Tg-cang-SE1553-Ab-1/ GM-Tg-cang-SE1553-Ab-2 | Anti-Canine JMJD8 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1553-Ab-1/ GM-Tg-bovg-SE1553-Ab-2 | Anti-Bovine JMJD8 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1553-Ab-1/ GM-Tg-equg-SE1553-Ab-2 | Anti-Equine JMJD8 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1553-Ab-1/ GM-Tg-hg-SE1553-Ab-2; GM-Tg-rg-SE1553-Ab-1/ GM-Tg-rg-SE1553-Ab-2; GM-Tg-mg-SE1553-Ab-1/ GM-Tg-mg-SE1553-Ab-2; GM-Tg-cynog-SE1553-Ab-1/ GM-Tg-cynog-SE1553-Ab-2; GM-Tg-felg-SE1553-Ab-1/ GM-Tg-felg-SE1553-Ab-2; GM-Tg-cang-SE1553-Ab-1/ GM-Tg-cang-SE1553-Ab-2; GM-Tg-bovg-SE1553-Ab-1/ GM-Tg-bovg-SE1553-Ab-2; GM-Tg-equg-SE1553-Ab-1/ GM-Tg-equg-SE1553-Ab-2 |
| Products Name | Anti-JMJD8 monoclonal antibody |
| Format | mab |
| Target Name | JMJD8 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-JMJD8 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1553-Ag-1 | Recombinant multi-species JMJD8/ C16orf20/ PP14397 protein |
Target information
| Target ID | GM-SE1553 |
| Target Name | JMJD8 |
| Gene ID | 339123,72106,360498,697226,490091,101092574,100139040,100147047 |
| Gene Symbol and Synonyms | 2610003J06Rik,C16orf20,JMJD8,PP14397,RGD1307381 |
| Uniprot Accession | Q96S16,Q6AY40 |
| Uniprot Entry Name | JMJD8_HUMAN,JMJD8_RAT |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000161999 |
| Target Classification | N/A |
The target: JMJD8, gene name: JMJD8, also named as C16orf20, PP14397. Involved in several processes, including positive regulation of I-kappaB kinase/NF-kappaB signaling; positive regulation of sprouting angiogenesis; and regulation of glycolytic process. Located in endoplasmic reticulum lumen and nucleus. [provided by Alliance of Genome Resources, Apr 2022].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
