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Anti-FCRLB/ FCRL2/ FCRLM2 functional antibody
Anti-FCRLB/ FCRL2/ FCRLM2 functional antibody for cell culture, ELISA & in-vivo assay
Go to FCRLB/FCRLB products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1557-Ab-1/ GM-Tg-hg-SE1557-Ab-2 | Anti-Human FCRLB monoclonal antibody | Human |
| GM-Tg-rg-SE1557-Ab-1/ GM-Tg-rg-SE1557-Ab-2 | Anti-Rat FCRLB monoclonal antibody | Rat |
| GM-Tg-mg-SE1557-Ab-1/ GM-Tg-mg-SE1557-Ab-2 | Anti-Mouse FCRLB monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1557-Ab-1/ GM-Tg-cynog-SE1557-Ab-2 | Anti-Cynomolgus/ Rhesus macaque FCRLB monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1557-Ab-1/ GM-Tg-felg-SE1557-Ab-2 | Anti-Feline FCRLB monoclonal antibody | Feline |
| GM-Tg-cang-SE1557-Ab-1/ GM-Tg-cang-SE1557-Ab-2 | Anti-Canine FCRLB monoclonal antibody | Canine |
| GM-Tg-bovg-SE1557-Ab-1/ GM-Tg-bovg-SE1557-Ab-2 | Anti-Bovine FCRLB monoclonal antibody | Bovine |
| GM-Tg-equg-SE1557-Ab-1/ GM-Tg-equg-SE1557-Ab-2 | Anti-Equine FCRLB monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1557-Ab-1/ GM-Tg-hg-SE1557-Ab-2; GM-Tg-rg-SE1557-Ab-1/ GM-Tg-rg-SE1557-Ab-2; GM-Tg-mg-SE1557-Ab-1/ GM-Tg-mg-SE1557-Ab-2; GM-Tg-cynog-SE1557-Ab-1/ GM-Tg-cynog-SE1557-Ab-2; GM-Tg-felg-SE1557-Ab-1/ GM-Tg-felg-SE1557-Ab-2; GM-Tg-cang-SE1557-Ab-1/ GM-Tg-cang-SE1557-Ab-2; GM-Tg-bovg-SE1557-Ab-1/ GM-Tg-bovg-SE1557-Ab-2; GM-Tg-equg-SE1557-Ab-1/ GM-Tg-equg-SE1557-Ab-2 |
| Products Name | Anti-FCRLB monoclonal antibody |
| Format | mab |
| Target Name | FCRLB |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-FCRLB benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1557-Ag-1 | Recombinant multi-species FCRLB/ FCRL2/ FCRLM2 protein |
Target information
| Target ID | GM-SE1557 |
| Target Name | FCRLB |
| Gene ID | 127943,435653,498275,720028,609689,101087040,522702,100147023 |
| Gene Symbol and Synonyms | FCRL2,FCRLB,FCRLM2,FCRLY,FcRY,FREB-2,FREB2,mFCRL2,RGD1563018 |
| Uniprot Accession | Q6BAA4 |
| Uniprot Entry Name | FCRLB_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000162746 |
| Target Classification | N/A |
The target: FCRLB, gene name: FCRLB, also named as FCRL2, FCRLM2, FCRLY, FREB-2, FREB2, FcRY. FCRL2 belongs to the Fc receptor family. Fc receptors are involved in phagocytosis, antibody-dependent cell cytotoxicity, immediate hypersensitivity, and transcytosis of immunoglobulins via their ability to bind immunoglobulin (Ig) constant regions (Chikaev et al., 2005 [PubMed 15676285]).[supplied by OMIM, Mar 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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