Anti-PPA6/ ACP6/ ACPL1 functional antibody

Anti-PPA6/ ACP6/ ACPL1 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to ACP6/ACP6 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1558-Ab-1/ GM-Tg-hg-SE1558-Ab-2Anti-Human ACP6 monoclonal antibodyHuman
GM-Tg-rg-SE1558-Ab-1/ GM-Tg-rg-SE1558-Ab-2Anti-Rat ACP6 monoclonal antibodyRat
GM-Tg-mg-SE1558-Ab-1/ GM-Tg-mg-SE1558-Ab-2Anti-Mouse ACP6 monoclonal antibodyMouse
GM-Tg-cynog-SE1558-Ab-1/ GM-Tg-cynog-SE1558-Ab-2Anti-Cynomolgus/ Rhesus macaque ACP6 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1558-Ab-1/ GM-Tg-felg-SE1558-Ab-2Anti-Feline ACP6 monoclonal antibodyFeline
GM-Tg-cang-SE1558-Ab-1/ GM-Tg-cang-SE1558-Ab-2Anti-Canine ACP6 monoclonal antibodyCanine
GM-Tg-bovg-SE1558-Ab-1/ GM-Tg-bovg-SE1558-Ab-2Anti-Bovine ACP6 monoclonal antibodyBovine
GM-Tg-equg-SE1558-Ab-1/ GM-Tg-equg-SE1558-Ab-2Anti-Equine ACP6 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1558-Ab-1/ GM-Tg-hg-SE1558-Ab-2; GM-Tg-rg-SE1558-Ab-1/ GM-Tg-rg-SE1558-Ab-2;
GM-Tg-mg-SE1558-Ab-1/ GM-Tg-mg-SE1558-Ab-2; GM-Tg-cynog-SE1558-Ab-1/ GM-Tg-cynog-SE1558-Ab-2;
GM-Tg-felg-SE1558-Ab-1/ GM-Tg-felg-SE1558-Ab-2; GM-Tg-cang-SE1558-Ab-1/ GM-Tg-cang-SE1558-Ab-2;
GM-Tg-bovg-SE1558-Ab-1/ GM-Tg-bovg-SE1558-Ab-2; GM-Tg-equg-SE1558-Ab-1/ GM-Tg-equg-SE1558-Ab-2
Products NameAnti-ACP6 monoclonal antibody
Formatmab
Target NameACP6
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-ACP6 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1558-Ag-1Recombinant multi-species PPA6/ ACP6/ ACPL1 protein


    Target information

    Target IDGM-SE1558
    Target NameACP6
    Gene ID51205,66659,295305,710431,475822,101093289,515738,100065568
    Gene Symbol and Synonyms5730559A09Rik,ACP6,ACPL1,LPAP,mPACPL1,PACPL1
    Uniprot AccessionQ9NPH0,A6H757
    Uniprot Entry NamePPA6_HUMAN,PPA6_BOVIN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000162836
    Target ClassificationN/A

    The target: ACP6, gene name: ACP6, also named as ACPL1, LPAP, PACPL1. This gene encodes a member of the histidine acid phosphatase protein family. The encoded protein hydrolyzes lysophosphatidic acid, which is involved in G protein-coupled receptor signaling, lipid raft modulation, and in balancing lipid composition within the cell. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2016].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.