Anti-CAHM4/ CALHM4/ C6orf78 functional antibody

Anti-CAHM4/ CALHM4/ C6orf78 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to CALHM4/CALHM4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1567-Ab-1/ GM-Tg-hg-SE1567-Ab-2Anti-Human CALHM4 monoclonal antibodyHuman
GM-Tg-rg-SE1567-Ab-1/ GM-Tg-rg-SE1567-Ab-2Anti-Rat CALHM4 monoclonal antibodyRat
GM-Tg-mg-SE1567-Ab-1/ GM-Tg-mg-SE1567-Ab-2Anti-Mouse CALHM4 monoclonal antibodyMouse
GM-Tg-cynog-SE1567-Ab-1/ GM-Tg-cynog-SE1567-Ab-2Anti-Cynomolgus/ Rhesus macaque CALHM4 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1567-Ab-1/ GM-Tg-felg-SE1567-Ab-2Anti-Feline CALHM4 monoclonal antibodyFeline
GM-Tg-cang-SE1567-Ab-1/ GM-Tg-cang-SE1567-Ab-2Anti-Canine CALHM4 monoclonal antibodyCanine
GM-Tg-bovg-SE1567-Ab-1/ GM-Tg-bovg-SE1567-Ab-2Anti-Bovine CALHM4 monoclonal antibodyBovine
GM-Tg-equg-SE1567-Ab-1/ GM-Tg-equg-SE1567-Ab-2Anti-Equine CALHM4 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1567-Ab-1/ GM-Tg-hg-SE1567-Ab-2; GM-Tg-rg-SE1567-Ab-1/ GM-Tg-rg-SE1567-Ab-2;
GM-Tg-mg-SE1567-Ab-1/ GM-Tg-mg-SE1567-Ab-2; GM-Tg-cynog-SE1567-Ab-1/ GM-Tg-cynog-SE1567-Ab-2;
GM-Tg-felg-SE1567-Ab-1/ GM-Tg-felg-SE1567-Ab-2; GM-Tg-cang-SE1567-Ab-1/ GM-Tg-cang-SE1567-Ab-2;
GM-Tg-bovg-SE1567-Ab-1/ GM-Tg-bovg-SE1567-Ab-2; GM-Tg-equg-SE1567-Ab-1/ GM-Tg-equg-SE1567-Ab-2
Products NameAnti-CALHM4 monoclonal antibody
Formatmab
Target NameCALHM4
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CALHM4 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1567-Ag-1Recombinant multi-species CAHM4/ CALHM4/ C6orf78 protein


    Target information

    Target IDGM-SE1567
    Target NameCALHM4
    Gene ID221301,270711,499445,715850,102155016,101089939,529412,100072689
    Gene Symbol and Synonyms4732454E20Rik,C6orf78,CALHM4,FAM26D,Gm643
    Uniprot AccessionQ5JW98
    Uniprot Entry NameCAHM4_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000164451
    Target ClassificationIon Channel

    The target: CALHM4, gene name: CALHM4, also named as C6orf78, FAM26D. Predicted to enable cation channel activity. Predicted to be involved in cation transmembrane transport. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.