Anti-STOX1/ C10orf24 functional antibody

Anti-STOX1/ C10orf24 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to STOX1/STOX1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1570-Ab-1/ GM-Tg-hg-SE1570-Ab-2Anti-Human STOX1 monoclonal antibodyHuman
GM-Tg-rg-SE1570-Ab-1/ GM-Tg-rg-SE1570-Ab-2Anti-Rat STOX1 monoclonal antibodyRat
GM-Tg-mg-SE1570-Ab-1/ GM-Tg-mg-SE1570-Ab-2Anti-Mouse STOX1 monoclonal antibodyMouse
GM-Tg-cynog-SE1570-Ab-1/ GM-Tg-cynog-SE1570-Ab-2Anti-Cynomolgus/ Rhesus macaque STOX1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1570-Ab-1/ GM-Tg-felg-SE1570-Ab-2Anti-Feline STOX1 monoclonal antibodyFeline
GM-Tg-cang-SE1570-Ab-1/ GM-Tg-cang-SE1570-Ab-2Anti-Canine STOX1 monoclonal antibodyCanine
GM-Tg-bovg-SE1570-Ab-1/ GM-Tg-bovg-SE1570-Ab-2Anti-Bovine STOX1 monoclonal antibodyBovine
GM-Tg-equg-SE1570-Ab-1/ GM-Tg-equg-SE1570-Ab-2Anti-Equine STOX1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1570-Ab-1/ GM-Tg-hg-SE1570-Ab-2; GM-Tg-rg-SE1570-Ab-1/ GM-Tg-rg-SE1570-Ab-2;
GM-Tg-mg-SE1570-Ab-1/ GM-Tg-mg-SE1570-Ab-2; GM-Tg-cynog-SE1570-Ab-1/ GM-Tg-cynog-SE1570-Ab-2;
GM-Tg-felg-SE1570-Ab-1/ GM-Tg-felg-SE1570-Ab-2; GM-Tg-cang-SE1570-Ab-1/ GM-Tg-cang-SE1570-Ab-2;
GM-Tg-bovg-SE1570-Ab-1/ GM-Tg-bovg-SE1570-Ab-2; GM-Tg-equg-SE1570-Ab-1/ GM-Tg-equg-SE1570-Ab-2
Products NameAnti-STOX1 monoclonal antibody
Formatmab
Target NameSTOX1
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-STOX1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1570-Ag-1Recombinant multi-species STOX1/ C10orf24 protein


    Target information

    Target IDGM-SE1570
    Target NameSTOX1
    Gene ID219736,216021,294388,717738,489017,101098165,506979,100072657
    Gene Symbol and Synonyms4732470K04Rik,C10orf24,Gm63,RGD1310622,STOX1
    Uniprot AccessionQ6ZVD7
    Uniprot Entry NameSTOX1_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000165730
    Target ClassificationN/A

    The target: STOX1, gene name: STOX1, also named as C10orf24. The protein encoded by this gene may function as a DNA binding protein. Mutations in this gene are associated with pre-eclampsia/eclampsia 4 (PEE4). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.