Anti-MET17/ METTL17/ METT11D1 functional antibody

Anti-MET17/ METTL17/ METT11D1 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to METTL17/METTL17 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1571-Ab-1/ GM-Tg-hg-SE1571-Ab-2Anti-Human METTL17 monoclonal antibodyHuman
GM-Tg-rg-SE1571-Ab-1/ GM-Tg-rg-SE1571-Ab-2Anti-Rat METTL17 monoclonal antibodyRat
GM-Tg-mg-SE1571-Ab-1/ GM-Tg-mg-SE1571-Ab-2Anti-Mouse METTL17 monoclonal antibodyMouse
GM-Tg-cynog-SE1571-Ab-1/ GM-Tg-cynog-SE1571-Ab-2Anti-Cynomolgus/ Rhesus macaque METTL17 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1571-Ab-1/ GM-Tg-felg-SE1571-Ab-2Anti-Feline METTL17 monoclonal antibodyFeline
GM-Tg-cang-SE1571-Ab-1/ GM-Tg-cang-SE1571-Ab-2Anti-Canine METTL17 monoclonal antibodyCanine
GM-Tg-bovg-SE1571-Ab-1/ GM-Tg-bovg-SE1571-Ab-2Anti-Bovine METTL17 monoclonal antibodyBovine
GM-Tg-equg-SE1571-Ab-1/ GM-Tg-equg-SE1571-Ab-2Anti-Equine METTL17 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1571-Ab-1/ GM-Tg-hg-SE1571-Ab-2; GM-Tg-rg-SE1571-Ab-1/ GM-Tg-rg-SE1571-Ab-2;
GM-Tg-mg-SE1571-Ab-1/ GM-Tg-mg-SE1571-Ab-2; GM-Tg-cynog-SE1571-Ab-1/ GM-Tg-cynog-SE1571-Ab-2;
GM-Tg-felg-SE1571-Ab-1/ GM-Tg-felg-SE1571-Ab-2; GM-Tg-cang-SE1571-Ab-1/ GM-Tg-cang-SE1571-Ab-2;
GM-Tg-bovg-SE1571-Ab-1/ GM-Tg-bovg-SE1571-Ab-2; GM-Tg-equg-SE1571-Ab-1/ GM-Tg-equg-SE1571-Ab-2
Products NameAnti-METTL17 monoclonal antibody
Formatmab
Target NameMETTL17
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-METTL17 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1571-Ag-1Recombinant multi-species MET17/ METTL17/ METT11D1 protein


    Target information

    Target IDGM-SE1571
    Target NameMETTL17
    Gene ID64745,52535,305845,705009,475396,101092441,514880,100072699
    Gene Symbol and Synonyms2310032K15Rik,D14Ertd209e,METT11D1,METTL17,RGD1559895
    Uniprot AccessionQ9H7H0,Q2TBP8
    Uniprot Entry NameMET17_HUMAN,MET17_BOVIN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000165792
    Target ClassificationN/A

    The target: METTL17, gene name: METTL17, also named as METT11D1. Predicted to enable S-adenosyl-L-methionine binding activity and mitochondrial ribosome binding activity. Predicted to be involved in ribosomal small subunit biogenesis. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.