Anti-TBX10/ TBX13/ TBX7 functional antibody

Anti-TBX10/ TBX13/ TBX7 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to TBX10/TBX10 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1583-Ab-1/ GM-Tg-hg-SE1583-Ab-2Anti-Human TBX10 monoclonal antibodyHuman
GM-Tg-rg-SE1583-Ab-1/ GM-Tg-rg-SE1583-Ab-2Anti-Rat TBX10 monoclonal antibodyRat
GM-Tg-mg-SE1583-Ab-1/ GM-Tg-mg-SE1583-Ab-2Anti-Mouse TBX10 monoclonal antibodyMouse
GM-Tg-cynog-SE1583-Ab-1/ GM-Tg-cynog-SE1583-Ab-2Anti-Cynomolgus/ Rhesus macaque TBX10 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1583-Ab-1/ GM-Tg-felg-SE1583-Ab-2Anti-Feline TBX10 monoclonal antibodyFeline
GM-Tg-cang-SE1583-Ab-1/ GM-Tg-cang-SE1583-Ab-2Anti-Canine TBX10 monoclonal antibodyCanine
GM-Tg-bovg-SE1583-Ab-1/ GM-Tg-bovg-SE1583-Ab-2Anti-Bovine TBX10 monoclonal antibodyBovine
GM-Tg-equg-SE1583-Ab-1/ GM-Tg-equg-SE1583-Ab-2Anti-Equine TBX10 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1583-Ab-1/ GM-Tg-hg-SE1583-Ab-2; GM-Tg-rg-SE1583-Ab-1/ GM-Tg-rg-SE1583-Ab-2;
GM-Tg-mg-SE1583-Ab-1/ GM-Tg-mg-SE1583-Ab-2; GM-Tg-cynog-SE1583-Ab-1/ GM-Tg-cynog-SE1583-Ab-2;
GM-Tg-felg-SE1583-Ab-1/ GM-Tg-felg-SE1583-Ab-2; GM-Tg-cang-SE1583-Ab-1/ GM-Tg-cang-SE1583-Ab-2;
GM-Tg-bovg-SE1583-Ab-1/ GM-Tg-bovg-SE1583-Ab-2; GM-Tg-equg-SE1583-Ab-1/ GM-Tg-equg-SE1583-Ab-2
Products NameAnti-TBX10 monoclonal antibody
Formatmab
Target NameTBX10
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-TBX10 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1583-Ag-1Recombinant multi-species TBX10/ TBX13/ TBX7 protein


    Target information

    Target IDGM-SE1583
    Target NameTBX10
    Gene ID347853,109575,688822,721689,618314,100147545
    Gene Symbol and SynonymsDc,TBX10,Tbx10-ps1,TBX13,TBX7
    Uniprot AccessionO75333
    Uniprot Entry NameTBX10_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000167800
    Target ClassificationN/A

    The target: TBX10, gene name: TBX10, also named as TBX13, TBX7. This gene encodes a member of the T-box family of transcription factors. These transcription factors share a DNA-binding domain called the T-box, and play a role in several developmental processes including early embryonic cell fate and organogenesis. The encoded protein is a member of the T-box 1 subfamily. Mutations in this gene are thought to be a cause of isolated cleft lip with or without cleft palate. [provided by RefSeq, Nov 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.