Anti-SNTB1/ 59-DAP/ A1B functional antibody

Anti-SNTB1/ 59-DAP/ A1B functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to SNTB1/SNTB1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1600-Ab-1/ GM-Tg-hg-SE1600-Ab-2Anti-Human SNTB1 monoclonal antibodyHuman
GM-Tg-rg-SE1600-Ab-1/ GM-Tg-rg-SE1600-Ab-2Anti-Rat SNTB1 monoclonal antibodyRat
GM-Tg-mg-SE1600-Ab-1/ GM-Tg-mg-SE1600-Ab-2Anti-Mouse SNTB1 monoclonal antibodyMouse
GM-Tg-cynog-SE1600-Ab-1/ GM-Tg-cynog-SE1600-Ab-2Anti-Cynomolgus/ Rhesus macaque SNTB1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1600-Ab-1/ GM-Tg-felg-SE1600-Ab-2Anti-Feline SNTB1 monoclonal antibodyFeline
GM-Tg-cang-SE1600-Ab-1/ GM-Tg-cang-SE1600-Ab-2Anti-Canine SNTB1 monoclonal antibodyCanine
GM-Tg-bovg-SE1600-Ab-1/ GM-Tg-bovg-SE1600-Ab-2Anti-Bovine SNTB1 monoclonal antibodyBovine
GM-Tg-equg-SE1600-Ab-1/ GM-Tg-equg-SE1600-Ab-2Anti-Equine SNTB1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1600-Ab-1/ GM-Tg-hg-SE1600-Ab-2; GM-Tg-rg-SE1600-Ab-1/ GM-Tg-rg-SE1600-Ab-2;
GM-Tg-mg-SE1600-Ab-1/ GM-Tg-mg-SE1600-Ab-2; GM-Tg-cynog-SE1600-Ab-1/ GM-Tg-cynog-SE1600-Ab-2;
GM-Tg-felg-SE1600-Ab-1/ GM-Tg-felg-SE1600-Ab-2; GM-Tg-cang-SE1600-Ab-1/ GM-Tg-cang-SE1600-Ab-2;
GM-Tg-bovg-SE1600-Ab-1/ GM-Tg-bovg-SE1600-Ab-2; GM-Tg-equg-SE1600-Ab-1/ GM-Tg-equg-SE1600-Ab-2
Products NameAnti-SNTB1 monoclonal antibody
Formatmab
Target NameSNTB1
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SNTB1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1600-Ag-1Recombinant multi-species SNTB1/ 59-DAP/ A1B protein


    Target information

    Target IDGM-SE1600
    Target NameSNTB1
    Gene ID6641,20649,299940,703245,482030,101082628,617927,100066500
    Gene Symbol and Synonyms59-DAP,A1B,BSYN2,DAPA1B,SNT2,SNT2B1,SNTB1,TIP-43
    Uniprot AccessionQ13884
    Uniprot Entry NameSNTB1_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000172164
    Target ClassificationN/A

    The target: SNTB1, gene name: SNTB1, also named as 59-DAP, A1B, BSYN2, DAPA1B, SNT2, SNT2B1, TIP-43. Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.