Anti-CATW/ CTSW/ LYPN functional antibody

Anti-CATW/ CTSW/ LYPN functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to CTSW/CTSW products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1601-Ab-1/ GM-Tg-hg-SE1601-Ab-2Anti-Human CTSW monoclonal antibodyHuman
GM-Tg-rg-SE1601-Ab-1/ GM-Tg-rg-SE1601-Ab-2Anti-Rat CTSW monoclonal antibodyRat
GM-Tg-mg-SE1601-Ab-1/ GM-Tg-mg-SE1601-Ab-2Anti-Mouse CTSW monoclonal antibodyMouse
GM-Tg-cynog-SE1601-Ab-1/ GM-Tg-cynog-SE1601-Ab-2Anti-Cynomolgus/ Rhesus macaque CTSW monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1601-Ab-1/ GM-Tg-felg-SE1601-Ab-2Anti-Feline CTSW monoclonal antibodyFeline
GM-Tg-cang-SE1601-Ab-1/ GM-Tg-cang-SE1601-Ab-2Anti-Canine CTSW monoclonal antibodyCanine
GM-Tg-bovg-SE1601-Ab-1/ GM-Tg-bovg-SE1601-Ab-2Anti-Bovine CTSW monoclonal antibodyBovine
GM-Tg-equg-SE1601-Ab-1/ GM-Tg-equg-SE1601-Ab-2Anti-Equine CTSW monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1601-Ab-1/ GM-Tg-hg-SE1601-Ab-2; GM-Tg-rg-SE1601-Ab-1/ GM-Tg-rg-SE1601-Ab-2;
GM-Tg-mg-SE1601-Ab-1/ GM-Tg-mg-SE1601-Ab-2; GM-Tg-cynog-SE1601-Ab-1/ GM-Tg-cynog-SE1601-Ab-2;
GM-Tg-felg-SE1601-Ab-1/ GM-Tg-felg-SE1601-Ab-2; GM-Tg-cang-SE1601-Ab-1/ GM-Tg-cang-SE1601-Ab-2;
GM-Tg-bovg-SE1601-Ab-1/ GM-Tg-bovg-SE1601-Ab-2; GM-Tg-equg-SE1601-Ab-1/ GM-Tg-equg-SE1601-Ab-2
Products NameAnti-CTSW monoclonal antibody
Formatmab
Target NameCTSW
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CTSW benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1601-Ag-1Recombinant multi-species CATW/ CTSW/ LYPN protein


    Target information

    Target IDGM-SE1601
    Target NameCTSW
    Gene ID1521,13041,293676,715505,483725,100144390,510967,100051806
    Gene Symbol and SynonymsCTSW,lymphopain,LYPN
    Uniprot AccessionP56202,Q9TST1
    Uniprot Entry NameCATW_HUMAN,CATW_FELCA
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000172543
    Target ClassificationN/A

    The target: CTSW, gene name: CTSW, also named as LYPN. The protein encoded by this gene, a member of the peptidase C1 family, is a cysteine proteinase that may have a specific function in the mechanism or regulation of T-cell cytolytic activity. The encoded protein is found associated with the membrane inside the endoplasmic reticulum of natural killer and cytotoxic T-cells. Expression of this gene is up-regulated by interleukin-2. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.