Anti-PAR15/ PARP15/ ARTD7 functional antibody

Anti-PAR15/ PARP15/ ARTD7 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to PARP15/PARP15 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1603-Ab-1/ GM-Tg-hg-SE1603-Ab-2Anti-Human PARP15 monoclonal antibodyHuman
GM-Tg-rg-SE1603-Ab-1/ GM-Tg-rg-SE1603-Ab-2Anti-Rat PARP15 monoclonal antibodyRat
GM-Tg-mg-SE1603-Ab-1/ GM-Tg-mg-SE1603-Ab-2Anti-Mouse PARP15 monoclonal antibodyMouse
GM-Tg-cynog-SE1603-Ab-1/ GM-Tg-cynog-SE1603-Ab-2Anti-Cynomolgus/ Rhesus macaque PARP15 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1603-Ab-1/ GM-Tg-felg-SE1603-Ab-2Anti-Feline PARP15 monoclonal antibodyFeline
GM-Tg-cang-SE1603-Ab-1/ GM-Tg-cang-SE1603-Ab-2Anti-Canine PARP15 monoclonal antibodyCanine
GM-Tg-bovg-SE1603-Ab-1/ GM-Tg-bovg-SE1603-Ab-2Anti-Bovine PARP15 monoclonal antibodyBovine
GM-Tg-equg-SE1603-Ab-1/ GM-Tg-equg-SE1603-Ab-2Anti-Equine PARP15 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1603-Ab-1/ GM-Tg-hg-SE1603-Ab-2; GM-Tg-rg-SE1603-Ab-1/ GM-Tg-rg-SE1603-Ab-2;
GM-Tg-mg-SE1603-Ab-1/ GM-Tg-mg-SE1603-Ab-2; GM-Tg-cynog-SE1603-Ab-1/ GM-Tg-cynog-SE1603-Ab-2;
GM-Tg-felg-SE1603-Ab-1/ GM-Tg-felg-SE1603-Ab-2; GM-Tg-cang-SE1603-Ab-1/ GM-Tg-cang-SE1603-Ab-2;
GM-Tg-bovg-SE1603-Ab-1/ GM-Tg-bovg-SE1603-Ab-2; GM-Tg-equg-SE1603-Ab-1/ GM-Tg-equg-SE1603-Ab-2
Products NameAnti-PARP15 monoclonal antibody
Formatmab
Target NamePARP15
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PARP15 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1603-Ag-1Recombinant multi-species PAR15/ PARP15/ ARTD7 protein


    Target information

    Target IDGM-SE1603
    Target NamePARP15
    Gene ID165631,715533,608662,101091391,100070587
    Gene Symbol and SynonymsARTD7,BAL3,PARP15,pART7
    Uniprot AccessionQ460N3
    Uniprot Entry NamePAR15_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000173200
    Target ClassificationN/A

    The target: PARP15, gene name: PARP15, also named as ARTD7, BAL3, pART7. PARP15 is a macrodomain-containing transcriptional repressor with poly(ADP-ribose) polymerase activity (Aguiar et al., 2005 [PubMed 16061477]).[supplied by OMIM, May 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.