Anti-LCORL/ MLR1 functional antibody

Anti-LCORL/ MLR1 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to LCORL/LCORL products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1620-Ab-1/ GM-Tg-hg-SE1620-Ab-2Anti-Human LCORL monoclonal antibodyHuman
GM-Tg-rg-SE1620-Ab-1/ GM-Tg-rg-SE1620-Ab-2Anti-Rat LCORL monoclonal antibodyRat
GM-Tg-mg-SE1620-Ab-1/ GM-Tg-mg-SE1620-Ab-2Anti-Mouse LCORL monoclonal antibodyMouse
GM-Tg-cynog-SE1620-Ab-1/ GM-Tg-cynog-SE1620-Ab-2Anti-Cynomolgus/ Rhesus macaque LCORL monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1620-Ab-1/ GM-Tg-felg-SE1620-Ab-2Anti-Feline LCORL monoclonal antibodyFeline
GM-Tg-cang-SE1620-Ab-1/ GM-Tg-cang-SE1620-Ab-2Anti-Canine LCORL monoclonal antibodyCanine
GM-Tg-bovg-SE1620-Ab-1/ GM-Tg-bovg-SE1620-Ab-2Anti-Bovine LCORL monoclonal antibodyBovine
GM-Tg-equg-SE1620-Ab-1/ GM-Tg-equg-SE1620-Ab-2Anti-Equine LCORL monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1620-Ab-1/ GM-Tg-hg-SE1620-Ab-2; GM-Tg-rg-SE1620-Ab-1/ GM-Tg-rg-SE1620-Ab-2;
GM-Tg-mg-SE1620-Ab-1/ GM-Tg-mg-SE1620-Ab-2; GM-Tg-cynog-SE1620-Ab-1/ GM-Tg-cynog-SE1620-Ab-2;
GM-Tg-felg-SE1620-Ab-1/ GM-Tg-felg-SE1620-Ab-2; GM-Tg-cang-SE1620-Ab-1/ GM-Tg-cang-SE1620-Ab-2;
GM-Tg-bovg-SE1620-Ab-1/ GM-Tg-bovg-SE1620-Ab-2; GM-Tg-equg-SE1620-Ab-1/ GM-Tg-equg-SE1620-Ab-2
Products NameAnti-LCORL monoclonal antibody
Formatmab
Target NameLCORL
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-LCORL benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1620-Ag-1Recombinant multi-species LCORL/ MLR1 protein


    Target information

    Target IDGM-SE1620
    Target NameLCORL
    Gene ID254251,209707,498385,715285,613008,101085286,540095,100068577
    Gene Symbol and SynonymsLCORL,LCORLp1,LCORLp2,MLR1,RGD1561241
    Uniprot AccessionQ8N3X6
    Uniprot Entry NameLCORL_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000178177
    Target ClassificationN/A

    The target: LCORL, gene name: LCORL, also named as MLR1. This gene encodes a transcription factor that appears to function in spermatogenesis. Polymorphisms in this gene are associated with measures of skeletal frame size and adult height. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.