Anti-LGALS7B/ GAL7/ Gal-7 functional antibody

Anti-LGALS7B/ GAL7/ Gal-7 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to LGALS7B/LGALS7B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1622-Ab-1/ GM-Tg-hg-SE1622-Ab-2Anti-Human LGALS7B monoclonal antibodyHuman
GM-Tg-rg-SE1622-Ab-1/ GM-Tg-rg-SE1622-Ab-2Anti-Rat LGALS7B monoclonal antibodyRat
GM-Tg-mg-SE1622-Ab-1/ GM-Tg-mg-SE1622-Ab-2Anti-Mouse LGALS7B monoclonal antibodyMouse
GM-Tg-cynog-SE1622-Ab-1/ GM-Tg-cynog-SE1622-Ab-2Anti-Cynomolgus/ Rhesus macaque LGALS7B monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1622-Ab-1/ GM-Tg-felg-SE1622-Ab-2Anti-Feline LGALS7B monoclonal antibodyFeline
GM-Tg-cang-SE1622-Ab-1/ GM-Tg-cang-SE1622-Ab-2Anti-Canine LGALS7B monoclonal antibodyCanine
GM-Tg-bovg-SE1622-Ab-1/ GM-Tg-bovg-SE1622-Ab-2Anti-Bovine LGALS7B monoclonal antibodyBovine
GM-Tg-equg-SE1622-Ab-1/ GM-Tg-equg-SE1622-Ab-2Anti-Equine LGALS7B monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1622-Ab-1/ GM-Tg-hg-SE1622-Ab-2; GM-Tg-rg-SE1622-Ab-1/ GM-Tg-rg-SE1622-Ab-2;
GM-Tg-mg-SE1622-Ab-1/ GM-Tg-mg-SE1622-Ab-2; GM-Tg-cynog-SE1622-Ab-1/ GM-Tg-cynog-SE1622-Ab-2;
GM-Tg-felg-SE1622-Ab-1/ GM-Tg-felg-SE1622-Ab-2; GM-Tg-cang-SE1622-Ab-1/ GM-Tg-cang-SE1622-Ab-2;
GM-Tg-bovg-SE1622-Ab-1/ GM-Tg-bovg-SE1622-Ab-2; GM-Tg-equg-SE1622-Ab-1/ GM-Tg-equg-SE1622-Ab-2
Products NameAnti-LGALS7B monoclonal antibody
Formatmab
Target NameLGALS7B
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-LGALS7B benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1622-Ag-1Recombinant multi-species LGALS7B/ GAL7/ Gal-7 protein


    Target information

    Target IDGM-SE1622
    Target NameLGALS7B
    Gene ID653499,119863963,101100430
    Gene Symbol and SynonymsGal-7,GAL7,HKL-14,LGALS7,LGALS7B,PI7
    Uniprot AccessionN/A
    Uniprot Entry Name
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000178934
    Target ClassificationN/A

    The target: LGALS7B, gene name: LGALS7B, also named as GAL7, Gal-7, HKL-14, LGALS7, PI7. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridization studies indicate that this lectin is specifically expressed in keratinocytes and found mainly in stratified squamous epithelium. A duplicate copy of this gene (GeneID:3963) is found adjacent to, but on the opposite strand on chromosome 19. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.