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Anti-FUCO/ FUCA1/ FUCA functional antibody
Anti-FUCO/ FUCA1/ FUCA functional antibody for cell culture, ELISA & in-vivo assay
Go to FUCA1/FUCA1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1623-Ab-1/ GM-Tg-hg-SE1623-Ab-2 | Anti-Human FUCA1 monoclonal antibody | Human |
| GM-Tg-rg-SE1623-Ab-1/ GM-Tg-rg-SE1623-Ab-2 | Anti-Rat FUCA1 monoclonal antibody | Rat |
| GM-Tg-mg-SE1623-Ab-1/ GM-Tg-mg-SE1623-Ab-2 | Anti-Mouse FUCA1 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1623-Ab-1/ GM-Tg-cynog-SE1623-Ab-2 | Anti-Cynomolgus/ Rhesus macaque FUCA1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1623-Ab-1/ GM-Tg-felg-SE1623-Ab-2 | Anti-Feline FUCA1 monoclonal antibody | Feline |
| GM-Tg-cang-SE1623-Ab-1/ GM-Tg-cang-SE1623-Ab-2 | Anti-Canine FUCA1 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1623-Ab-1/ GM-Tg-bovg-SE1623-Ab-2 | Anti-Bovine FUCA1 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1623-Ab-1/ GM-Tg-equg-SE1623-Ab-2 | Anti-Equine FUCA1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1623-Ab-1/ GM-Tg-hg-SE1623-Ab-2; GM-Tg-rg-SE1623-Ab-1/ GM-Tg-rg-SE1623-Ab-2; GM-Tg-mg-SE1623-Ab-1/ GM-Tg-mg-SE1623-Ab-2; GM-Tg-cynog-SE1623-Ab-1/ GM-Tg-cynog-SE1623-Ab-2; GM-Tg-felg-SE1623-Ab-1/ GM-Tg-felg-SE1623-Ab-2; GM-Tg-cang-SE1623-Ab-1/ GM-Tg-cang-SE1623-Ab-2; GM-Tg-bovg-SE1623-Ab-1/ GM-Tg-bovg-SE1623-Ab-2; GM-Tg-equg-SE1623-Ab-1/ GM-Tg-equg-SE1623-Ab-2 |
| Products Name | Anti-FUCA1 monoclonal antibody |
| Format | mab |
| Target Name | FUCA1 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-FUCA1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1623-Ag-1 | Recombinant multi-species FUCO/ FUCA1/ FUCA protein |
| ORF Viral Vector | pGMLPm004914 | mouse Fuca1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm004914 | mouse Fuca1 Lentivirus particle |
Target information
| Target ID | GM-SE1623 |
| Target Name | FUCA1 |
| Gene ID | 2517,71665,24375,710993,403929,101099988,509522,100071543 |
| Gene Symbol and Synonyms | 0610006A03Rik,9530055J05Rik,Afuc,FUCA,FUCA1 |
| Uniprot Accession | P04066,P17164,P48300,Q2KIM0 |
| Uniprot Entry Name | FUCO_HUMAN,FUCO_RAT,FUCO_CANLF,FUCO_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000179163 |
| Target Classification | N/A |
The target: FUCA1, gene name: FUCA1, also named as FUCA. The protein encoded by this gene is a lysosomal enzyme involved in the degradation of fucose-containing glycoproteins and glycolipids. Mutations in this gene are associated with fucosidosis (FUCA1D), which is an autosomal recessive lysosomal storage disease. A pseudogene of this locus is present on chr 2.[provided by RefSeq, Oct 2009].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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