Anti-BAG6/ BAG-6/ BAT3 functional antibody

Anti-BAG6/ BAG-6/ BAT3 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to BAG6/BAG6 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1653-Ab-1/ GM-Tg-hg-SE1653-Ab-2Anti-Human BAG6 monoclonal antibodyHuman
GM-Tg-rg-SE1653-Ab-1/ GM-Tg-rg-SE1653-Ab-2Anti-Rat BAG6 monoclonal antibodyRat
GM-Tg-mg-SE1653-Ab-1/ GM-Tg-mg-SE1653-Ab-2Anti-Mouse BAG6 monoclonal antibodyMouse
GM-Tg-cynog-SE1653-Ab-1/ GM-Tg-cynog-SE1653-Ab-2Anti-Cynomolgus/ Rhesus macaque BAG6 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1653-Ab-1/ GM-Tg-felg-SE1653-Ab-2Anti-Feline BAG6 monoclonal antibodyFeline
GM-Tg-cang-SE1653-Ab-1/ GM-Tg-cang-SE1653-Ab-2Anti-Canine BAG6 monoclonal antibodyCanine
GM-Tg-bovg-SE1653-Ab-1/ GM-Tg-bovg-SE1653-Ab-2Anti-Bovine BAG6 monoclonal antibodyBovine
GM-Tg-equg-SE1653-Ab-1/ GM-Tg-equg-SE1653-Ab-2Anti-Equine BAG6 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1653-Ab-1/ GM-Tg-hg-SE1653-Ab-2; GM-Tg-rg-SE1653-Ab-1/ GM-Tg-rg-SE1653-Ab-2;
GM-Tg-mg-SE1653-Ab-1/ GM-Tg-mg-SE1653-Ab-2; GM-Tg-cynog-SE1653-Ab-1/ GM-Tg-cynog-SE1653-Ab-2;
GM-Tg-felg-SE1653-Ab-1/ GM-Tg-felg-SE1653-Ab-2; GM-Tg-cang-SE1653-Ab-1/ GM-Tg-cang-SE1653-Ab-2;
GM-Tg-bovg-SE1653-Ab-1/ GM-Tg-bovg-SE1653-Ab-2; GM-Tg-equg-SE1653-Ab-1/ GM-Tg-equg-SE1653-Ab-2
Products NameAnti-BAG6 monoclonal antibody
Formatmab
Target NameBAG6
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-BAG6 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1653-Ag-1Recombinant multi-species BAG6/ BAG-6/ BAT3 protein
    ORF Viral VectorvGMLP005104human BAG6 Lentivirus particle
    ORF Viral VectorpGMLP005104human BAG6 Lentivirus plasmid


    Target information

    Target IDGM-SE1653
    Target NameBAG6
    Gene ID7917,224727,94342,720485,474842,101086144,508605,100050296
    Gene Symbol and Synonyms2410045D21Rik,BAG-6,BAG6,BAT3,D17H6S52E,D6S52E,G3,Scythe
    Uniprot AccessionP46379,Q6MG49
    Uniprot Entry NameBAG6_HUMAN,BAG6_RAT
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000204463
    Target ClassificationN/A

    The target: BAG6, gene name: BAG6, also named as BAG-6, BAT3, D6S52E, G3. This gene was first characterized as part of a cluster of genes located within the human major histocompatibility complex class III region. This gene encodes a nuclear protein that is cleaved by caspase 3 and is implicated in the control of apoptosis. In addition, the protein forms a complex with E1A binding protein p300 and is required for the acetylation of p53 in response to DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.