Anti-CATO/ CTSO/ CTSO1 functional antibody

Anti-CATO/ CTSO/ CTSO1 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to CTSO/CTSO products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1668-Ab-1/ GM-Tg-hg-SE1668-Ab-2Anti-Human CTSO monoclonal antibodyHuman
GM-Tg-rg-SE1668-Ab-1/ GM-Tg-rg-SE1668-Ab-2Anti-Rat CTSO monoclonal antibodyRat
GM-Tg-mg-SE1668-Ab-1/ GM-Tg-mg-SE1668-Ab-2Anti-Mouse CTSO monoclonal antibodyMouse
GM-Tg-cynog-SE1668-Ab-1/ GM-Tg-cynog-SE1668-Ab-2Anti-Cynomolgus/ Rhesus macaque CTSO monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1668-Ab-1/ GM-Tg-felg-SE1668-Ab-2Anti-Feline CTSO monoclonal antibodyFeline
GM-Tg-cang-SE1668-Ab-1/ GM-Tg-cang-SE1668-Ab-2Anti-Canine CTSO monoclonal antibodyCanine
GM-Tg-bovg-SE1668-Ab-1/ GM-Tg-bovg-SE1668-Ab-2Anti-Bovine CTSO monoclonal antibodyBovine
GM-Tg-equg-SE1668-Ab-1/ GM-Tg-equg-SE1668-Ab-2Anti-Equine CTSO monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1668-Ab-1/ GM-Tg-hg-SE1668-Ab-2; GM-Tg-rg-SE1668-Ab-1/ GM-Tg-rg-SE1668-Ab-2;
GM-Tg-mg-SE1668-Ab-1/ GM-Tg-mg-SE1668-Ab-2; GM-Tg-cynog-SE1668-Ab-1/ GM-Tg-cynog-SE1668-Ab-2;
GM-Tg-felg-SE1668-Ab-1/ GM-Tg-felg-SE1668-Ab-2; GM-Tg-cang-SE1668-Ab-1/ GM-Tg-cang-SE1668-Ab-2;
GM-Tg-bovg-SE1668-Ab-1/ GM-Tg-bovg-SE1668-Ab-2; GM-Tg-equg-SE1668-Ab-1/ GM-Tg-equg-SE1668-Ab-2
Products NameAnti-CTSO monoclonal antibody
Formatmab
Target NameCTSO
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CTSO benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1668-Ag-1Recombinant multi-species CATO/ CTSO/ CTSO1 protein


    Target information

    Target IDGM-SE1668
    Target NameCTSO
    Gene ID1519,229445,684529,699868,482665,101090686,616804,100069500
    Gene Symbol and SynonymsA330105D01Rik,CTSO,CTSO1
    Uniprot AccessionP43234
    Uniprot Entry NameCATO_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000256043
    Target ClassificationN/A

    The target: CTSO, gene name: CTSO, also named as CTSO1. The protein encoded by the gene is a cysteine proteinase and a member of the papain superfamily. This proteolytic enzyme is involved in cellular protein degradation and turnover. The recombinant form of this enzyme was shown to degrade synthetic peptides typically used as substrates for cysteine proteinases and its proteolytic activity was abolished by an inhibitor of cyteine proteinase. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.