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Anti-TN13B/ TNFSF13B/ BAFF monoclonal antibody
Anti-TN13B/ TNFSF13B/ BAFF antibody for FACS & in-vivo assay
Go to TNFSF13B/TNFSF13B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T02318-Ab-1/ GM-Tg-hg-T02318-Ab-2 | Anti-Human TNFSF13B monoclonal antibody | Human |
| GM-Tg-rg-T02318-Ab-1/ GM-Tg-rg-T02318-Ab-2 | Anti-Rat TNFSF13B monoclonal antibody | Rat |
| GM-Tg-mg-T02318-Ab-1/ GM-Tg-mg-T02318-Ab-2 | Anti-Mouse TNFSF13B monoclonal antibody | Mouse |
| GM-Tg-cynog-T02318-Ab-1/ GM-Tg-cynog-T02318-Ab-2 | Anti-Cynomolgus/ Rhesus macaque TNFSF13B monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T02318-Ab-1/ GM-Tg-felg-T02318-Ab-2 | Anti-Feline TNFSF13B monoclonal antibody | Feline |
| GM-Tg-cang-T02318-Ab-1/ GM-Tg-cang-T02318-Ab-2 | Anti-Canine TNFSF13B monoclonal antibody | Canine |
| GM-Tg-bovg-T02318-Ab-1/ GM-Tg-bovg-T02318-Ab-2 | Anti-Bovine TNFSF13B monoclonal antibody | Bovine |
| GM-Tg-equg-T02318-Ab-1/ GM-Tg-equg-T02318-Ab-2 | Anti-Equine TNFSF13B monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T02318-Ab-1/ GM-Tg-hg-T02318-Ab-2; GM-Tg-rg-T02318-Ab-1/ GM-Tg-rg-T02318-Ab-2; GM-Tg-mg-T02318-Ab-1/ GM-Tg-mg-T02318-Ab-2; GM-Tg-cynog-T02318-Ab-1/ GM-Tg-cynog-T02318-Ab-2; GM-Tg-felg-T02318-Ab-1/ GM-Tg-felg-T02318-Ab-2; GM-Tg-cang-T02318-Ab-1/ GM-Tg-cang-T02318-Ab-2; GM-Tg-bovg-T02318-Ab-1/ GM-Tg-bovg-T02318-Ab-2; GM-Tg-equg-T02318-Ab-1/ GM-Tg-equg-T02318-Ab-2 |
| Products Name | Anti-TNFSF13B monoclonal antibody |
| Format | mab |
| Target Name | TNFSF13B |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-TNFSF13B benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Target information
| Target ID | GM-T02318 |
| Target Name | TNFSF13B |
| Gene ID | 10673,24099,498666,693917,485545,101088640,504507,100051550 |
| Gene Symbol and Synonyms | BAFF,BLYS,CD257,D8Ertd387e,DTL,RGD1561519,TALL-1,TALL1,THANK,TNFSF13B,TNFSF20,TNLG7A,ZTNF4 |
| Uniprot Accession | Q9Y275 |
| Uniprot Entry Name | TN13B_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target, INN Index, Cytokine Target |
| Disease | Lupus Glomerulonephritis |
| Gene Ensembl | ENSG00000102524 |
| Target Classification | N/A |
The target: TNFSF13B, gene name: TNFSF13B, also named as BAFF, BLYS, CD257, DTL, TALL-1, TALL1, THANK, TNFSF20, TNLG7A, ZTNF4. The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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