Anti-NOS2 monoclonal antibody

Pre-made anti-NOS2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to NOS2/NOS2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T02703-Ab-1/ GM-Tg-hg-T02703-Ab-2Anti-Human NOS2 monoclonal antibodyHuman
GM-Tg-rg-T02703-Ab-1/ GM-Tg-rg-T02703-Ab-2Anti-Rat NOS2 monoclonal antibodyRat
GM-Tg-mg-T02703-Ab-1/ GM-Tg-mg-T02703-Ab-2Anti-Mouse NOS2 monoclonal antibodyMouse
GM-Tg-cynog-T02703-Ab-1/ GM-Tg-cynog-T02703-Ab-2Anti-Cynomolgus/ Rhesus macaque NOS2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T02703-Ab-1/ GM-Tg-felg-T02703-Ab-2Anti-Feline NOS2 monoclonal antibodyFeline
GM-Tg-cang-T02703-Ab-1/ GM-Tg-cang-T02703-Ab-2Anti-Canine NOS2 monoclonal antibodyCanine
GM-Tg-bovg-T02703-Ab-1/ GM-Tg-bovg-T02703-Ab-2Anti-Bovine NOS2 monoclonal antibodyBovine
GM-Tg-equg-T02703-Ab-1/ GM-Tg-equg-T02703-Ab-2Anti-Equine NOS2 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T02703-Ab-1/ GM-Tg-hg-T02703-Ab-2; GM-Tg-rg-T02703-Ab-1/ GM-Tg-rg-T02703-Ab-2;
GM-Tg-mg-T02703-Ab-1/ GM-Tg-mg-T02703-Ab-2; GM-Tg-cynog-T02703-Ab-1/ GM-Tg-cynog-T02703-Ab-2;
GM-Tg-felg-T02703-Ab-1/ GM-Tg-felg-T02703-Ab-2; GM-Tg-cang-T02703-Ab-1/ GM-Tg-cang-T02703-Ab-2;
GM-Tg-bovg-T02703-Ab-1/ GM-Tg-bovg-T02703-Ab-2; GM-Tg-equg-T02703-Ab-1/ GM-Tg-equg-T02703-Ab-2
Products NameAnti-NOS2 monoclonal antibody
Formatmab
Target NameNOS2
Protein Sub-locationIntrocelluar Protein
Category of antibodyTherapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-NOS2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-T02703-Ag-1Recombinant multi-species NOS2/ HEP-NOS/ INOS protein
    ORF Viral VectorpGMLV000143mouse Nos2 Lentivirus plasmid
    ORF Viral VectorvGMLV000143mouse Nos2 Lentivirus particle


    Target information

    Target IDGM-T02703
    Target NameNOS2
    Gene ID4843,18126,24599,706921,403822,101087020,282876,791246
    Gene Symbol and SynonymsHEP-NOS,i-NOS,INOS,MAC-NOS,NOS,Nos-2,NOS-II,NOS2,NOS2A
    Uniprot AccessionP35228,Q06518,O46660,O62699,Q27995
    Uniprot Entry NameNOS2_HUMAN,NOS2_MACMU,NOS2_RAT,NOS2_CANLF,NOS2_BOVIN
    Protein Sub-locationIntrocelluar Protein
    CategoryTherapeutics Target
    DiseaseCancer
    Gene EnsemblENSG00000007171
    Target ClassificationTumor-associated antigen (TAA)

    The target: NOS2, gene name: NOS2, also named as HEP-NOS, INOS, NOSA, NOS2. Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.