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Anti-RSK3 monoclonal antibody
Pre-made anti-RSK3 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to RSK3/RPS6KA3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T03279-Ab-1/ GM-Tg-hg-T03279-Ab-2 | Anti-Human RSK3/RPS6KA3 monoclonal antibody | Human |
| GM-Tg-rg-T03279-Ab-1/ GM-Tg-rg-T03279-Ab-2 | Anti-Rat RSK3/RPS6KA3 monoclonal antibody | Rat |
| GM-Tg-mg-T03279-Ab-1/ GM-Tg-mg-T03279-Ab-2 | Anti-Mouse RSK3/RPS6KA3 monoclonal antibody | Mouse |
| GM-Tg-cynog-T03279-Ab-1/ GM-Tg-cynog-T03279-Ab-2 | Anti-Cynomolgus/ Rhesus macaque RSK3/RPS6KA3 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T03279-Ab-1/ GM-Tg-felg-T03279-Ab-2 | Anti-Feline RSK3/RPS6KA3 monoclonal antibody | Feline |
| GM-Tg-cang-T03279-Ab-1/ GM-Tg-cang-T03279-Ab-2 | Anti-Canine RSK3/RPS6KA3 monoclonal antibody | Canine |
| GM-Tg-bovg-T03279-Ab-1/ GM-Tg-bovg-T03279-Ab-2 | Anti-Bovine RSK3/RPS6KA3 monoclonal antibody | Bovine |
| GM-Tg-equg-T03279-Ab-1/ GM-Tg-equg-T03279-Ab-2 | Anti-Equine RSK3/RPS6KA3 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T03279-Ab-1/ GM-Tg-hg-T03279-Ab-2; GM-Tg-rg-T03279-Ab-1/ GM-Tg-rg-T03279-Ab-2; GM-Tg-mg-T03279-Ab-1/ GM-Tg-mg-T03279-Ab-2; GM-Tg-cynog-T03279-Ab-1/ GM-Tg-cynog-T03279-Ab-2; GM-Tg-felg-T03279-Ab-1/ GM-Tg-felg-T03279-Ab-2; GM-Tg-cang-T03279-Ab-1/ GM-Tg-cang-T03279-Ab-2; GM-Tg-bovg-T03279-Ab-1/ GM-Tg-bovg-T03279-Ab-2; GM-Tg-equg-T03279-Ab-1/ GM-Tg-equg-T03279-Ab-2 |
| Products Name | Anti-RSK3/RPS6KA3 monoclonal antibody |
| Format | mab |
| Target Name | RSK3 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-RSK3 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T03279-Ag-1 | Recombinant multi-species KS6A3/ RSK3/ RPS6KA3 protein |
| ORF Viral Vector | pGMAP000548 | Human RPS6KA3 Adenovirus plasmid |
| ORF Viral Vector | vGMAP000548 | Human RPS6KA3 Adenovirus particle |
| ORF Viral Vector | pGMLPm004778 | mouse Rps6ka3 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm004778 | mouse Rps6ka3 Lentivirus particle |
Target information
| Target ID | GM-T03279 |
| Target Name | RSK3 |
| Gene ID | 6197,110651,501560,696825,119868388,101082546,511190,100058911 |
| Gene Symbol and Synonyms | CLS,HU-3,ISPK-1,MAPKAPK-1b,MAPKAPK1B,MPK-9,MRX19,p90-RSK2,p90RSK3,pp90RSK2,RGD1563860,RPS6KA3,RSK,RSK2,S6K-alpha3,XLID19 |
| Uniprot Accession | P51812 |
| Uniprot Entry Name | KS6A3_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000177189 |
| Target Classification | Kinase |
The target: RSK3, gene name: RPS6KA3, also named as CLS, HU-3, ISPK-1, MAPKAPK1B, MRX19, RSK, RSK2, S6K-alpha3, p90-RSK2, pp90RSK2. This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS). [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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