Anti-ADAM9/ CORD9/ MCMP functional antibody

Anti-ADAM9/ CORD9/ MCMP functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to ADAM9/ADAM9 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T03672-Ab-1/ GM-Tg-hg-T03672-Ab-2Anti-Human ADAM9 monoclonal antibodyHuman
GM-Tg-rg-T03672-Ab-1/ GM-Tg-rg-T03672-Ab-2Anti-Rat ADAM9 monoclonal antibodyRat
GM-Tg-mg-T03672-Ab-1/ GM-Tg-mg-T03672-Ab-2Anti-Mouse ADAM9 monoclonal antibodyMouse
GM-Tg-cynog-T03672-Ab-1/ GM-Tg-cynog-T03672-Ab-2Anti-Cynomolgus/ Rhesus macaque ADAM9 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T03672-Ab-1/ GM-Tg-felg-T03672-Ab-2Anti-Feline ADAM9 monoclonal antibodyFeline
GM-Tg-cang-T03672-Ab-1/ GM-Tg-cang-T03672-Ab-2Anti-Canine ADAM9 monoclonal antibodyCanine
GM-Tg-bovg-T03672-Ab-1/ GM-Tg-bovg-T03672-Ab-2Anti-Bovine ADAM9 monoclonal antibodyBovine
GM-Tg-equg-T03672-Ab-1/ GM-Tg-equg-T03672-Ab-2Anti-Equine ADAM9 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T03672-Ab-1/ GM-Tg-hg-T03672-Ab-2; GM-Tg-rg-T03672-Ab-1/ GM-Tg-rg-T03672-Ab-2;
GM-Tg-mg-T03672-Ab-1/ GM-Tg-mg-T03672-Ab-2; GM-Tg-cynog-T03672-Ab-1/ GM-Tg-cynog-T03672-Ab-2;
GM-Tg-felg-T03672-Ab-1/ GM-Tg-felg-T03672-Ab-2; GM-Tg-cang-T03672-Ab-1/ GM-Tg-cang-T03672-Ab-2;
GM-Tg-bovg-T03672-Ab-1/ GM-Tg-bovg-T03672-Ab-2; GM-Tg-equg-T03672-Ab-1/ GM-Tg-equg-T03672-Ab-2
Products NameAnti-ADAM9 monoclonal antibody
Formatmab
Target NameADAM9
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-ADAM9 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-T03672-Ag-1Recombinant multi-species ADAM9/ CORD9/ MCMP protein


    Target information

    Target IDGM-T03672
    Target NameADAM9
    Gene ID8754,11502,290834,701124,475579,101084619,281600,100058578
    Gene Symbol and SynonymsADAM9,CORD9,MCMP,MDC9,mKIAA0021,Mltng
    Uniprot AccessionQ13443
    Uniprot Entry NameADAM9_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    CategoryTherapeutics Target, Immuno-oncology Target
    DiseaseCancer
    Gene EnsemblENSG00000168615
    Target ClassificationCheckpoint-Immuno Oncology, Tumor-associated antigen (TAA)

    The target: ADAM9, gene name: ADAM9, also named as CORD9, MCMP, MDC9, Mltng. This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. Several alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jul 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.