Anti-ZA2G/ AZGP1/ ZAG functional antibody

Anti-ZA2G/ AZGP1/ ZAG functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to AZGP1/AZGP1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T05249-Ab-1/ GM-Tg-hg-T05249-Ab-2Anti-Human AZGP1 monoclonal antibodyHuman
GM-Tg-rg-T05249-Ab-1/ GM-Tg-rg-T05249-Ab-2Anti-Rat AZGP1 monoclonal antibodyRat
GM-Tg-mg-T05249-Ab-1/ GM-Tg-mg-T05249-Ab-2Anti-Mouse AZGP1 monoclonal antibodyMouse
GM-Tg-cynog-T05249-Ab-1/ GM-Tg-cynog-T05249-Ab-2Anti-Cynomolgus/ Rhesus macaque AZGP1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T05249-Ab-1/ GM-Tg-felg-T05249-Ab-2Anti-Feline AZGP1 monoclonal antibodyFeline
GM-Tg-cang-T05249-Ab-1/ GM-Tg-cang-T05249-Ab-2Anti-Canine AZGP1 monoclonal antibodyCanine
GM-Tg-bovg-T05249-Ab-1/ GM-Tg-bovg-T05249-Ab-2Anti-Bovine AZGP1 monoclonal antibodyBovine
GM-Tg-equg-T05249-Ab-1/ GM-Tg-equg-T05249-Ab-2Anti-Equine AZGP1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T05249-Ab-1/ GM-Tg-hg-T05249-Ab-2; GM-Tg-rg-T05249-Ab-1/ GM-Tg-rg-T05249-Ab-2;
GM-Tg-mg-T05249-Ab-1/ GM-Tg-mg-T05249-Ab-2; GM-Tg-cynog-T05249-Ab-1/ GM-Tg-cynog-T05249-Ab-2;
GM-Tg-felg-T05249-Ab-1/ GM-Tg-felg-T05249-Ab-2; GM-Tg-cang-T05249-Ab-1/ GM-Tg-cang-T05249-Ab-2;
GM-Tg-bovg-T05249-Ab-1/ GM-Tg-bovg-T05249-Ab-2; GM-Tg-equg-T05249-Ab-1/ GM-Tg-equg-T05249-Ab-2
Products NameAnti-AZGP1 monoclonal antibody
Formatmab
Target NameAZGP1
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-AZGP1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-T05249-Ag-1Recombinant multi-species ZA2G/ AZGP1/ ZAG protein
    ORF Viral VectorvGMAAV000018human AZGP1 AAV particle
    ORF Viral VectorpGMAAV000018human AZGP1 AAV plasmid
    ORF Viral VectorpGMAD000536house mouse Azgp1 Adenovirus plasmid
    ORF Viral VectorpGMAAV000065rat Azgp1 AAV plasmid
    ORF Viral VectorpGMAAV000067mouse Azgp1 AAV plasmid
    ORF Viral VectorvGMAD000536house mouse Azgp1 Adenovirus particle
    ORF Viral VectorvGMAAV000065rat Azgp1 AAV particle
    ORF Viral VectorvGMAAV000067mouse Azgp1 AAV particle


    Target information

    Target IDGM-T05249
    Target NameAZGP1
    Gene ID563,12007,25294,710136,479739,101097692,508800,100067197
    Gene Symbol and SynonymsAZGP1,ZA2G,ZA2GA,ZAG,Zna2gp
    Uniprot AccessionP25311,Q63678,Q3ZCH5
    Uniprot Entry NameZA2G_HUMAN,ZA2G_RAT,ZA2G_BOVIN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    CategoryTherapeutics Target
    DiseaseProstate Cancer
    Gene EnsemblENSG00000160862
    Target ClassificationN/A

    The target: AZGP1, gene name: AZGP1, also named as ZA2G, ZAG. Involved in cell adhesion and detection of chemical stimulus involved in sensory perception of bitter taste. Located in extracellular space. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.