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Anti-CGB3/ CG-beta/ CGB functional antibody
Anti-CGB3/ CG-beta/ CGB functional antibody for cell culture, ELISA & in-vivo assay
Go to CG-beta/CGB3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T06575-Ab-1/ GM-Tg-hg-T06575-Ab-2 | Anti-Human CG-beta/CGB3 monoclonal antibody | Human |
| GM-Tg-rg-T06575-Ab-1/ GM-Tg-rg-T06575-Ab-2 | Anti-Rat CG-beta/CGB3 monoclonal antibody | Rat |
| GM-Tg-mg-T06575-Ab-1/ GM-Tg-mg-T06575-Ab-2 | Anti-Mouse CG-beta/CGB3 monoclonal antibody | Mouse |
| GM-Tg-cynog-T06575-Ab-1/ GM-Tg-cynog-T06575-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CG-beta/CGB3 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T06575-Ab-1/ GM-Tg-felg-T06575-Ab-2 | Anti-Feline CG-beta/CGB3 monoclonal antibody | Feline |
| GM-Tg-cang-T06575-Ab-1/ GM-Tg-cang-T06575-Ab-2 | Anti-Canine CG-beta/CGB3 monoclonal antibody | Canine |
| GM-Tg-bovg-T06575-Ab-1/ GM-Tg-bovg-T06575-Ab-2 | Anti-Bovine CG-beta/CGB3 monoclonal antibody | Bovine |
| GM-Tg-equg-T06575-Ab-1/ GM-Tg-equg-T06575-Ab-2 | Anti-Equine CG-beta/CGB3 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T06575-Ab-1/ GM-Tg-hg-T06575-Ab-2; GM-Tg-rg-T06575-Ab-1/ GM-Tg-rg-T06575-Ab-2; GM-Tg-mg-T06575-Ab-1/ GM-Tg-mg-T06575-Ab-2; GM-Tg-cynog-T06575-Ab-1/ GM-Tg-cynog-T06575-Ab-2; GM-Tg-felg-T06575-Ab-1/ GM-Tg-felg-T06575-Ab-2; GM-Tg-cang-T06575-Ab-1/ GM-Tg-cang-T06575-Ab-2; GM-Tg-bovg-T06575-Ab-1/ GM-Tg-bovg-T06575-Ab-2; GM-Tg-equg-T06575-Ab-1/ GM-Tg-equg-T06575-Ab-2 |
| Products Name | Anti-CG-beta/CGB3 monoclonal antibody |
| Format | mab |
| Target Name | CG-beta |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CG-beta benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T06575-Ag-1 | Recombinant multi-species CGB3/ CG-beta/ CGB protein |
| ORF Viral Vector | vGMLP001861 | human CGB3 Lentivirus particle |
| ORF Viral Vector | pGMLP000845 | human CGB3 Lentivirus plasmid |
| ORF Viral Vector | vGMAP000262 | Human CGB Adenovirus particle |
| ORF Viral Vector | pGMLP001861 | human CGB3 Lentivirus plasmid |
| ORF Viral Vector | pGMAP000262 | Human CGB Adenovirus plasmid |
| ORF Viral Vector | vGMLP000845 | human CGB3 Lentivirus particle |
Target information
| Target ID | GM-T06575 |
| Target Name | CG-beta |
| Gene ID | 1082 |
| Gene Symbol and Synonyms | CGB,CGB3,CGB5,CGB7,CGB8,hCGB,LHB |
| Uniprot Accession | P0DN86 |
| Uniprot Entry Name | CGB3_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000104827 |
| Target Classification | N/A |
The target: CG-beta, gene name: CGB3, also named as CGB, CGB5, CGB7, CGB8, hCGB. This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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