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Anti-USP13 monoclonal antibody
Pre-made anti-USP13 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to USP13/USP13 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T07584-Ab-1/ GM-Tg-hg-T07584-Ab-2 | Anti-Human USP13 monoclonal antibody | Human |
| GM-Tg-rg-T07584-Ab-1/ GM-Tg-rg-T07584-Ab-2 | Anti-Rat USP13 monoclonal antibody | Rat |
| GM-Tg-mg-T07584-Ab-1/ GM-Tg-mg-T07584-Ab-2 | Anti-Mouse USP13 monoclonal antibody | Mouse |
| GM-Tg-cynog-T07584-Ab-1/ GM-Tg-cynog-T07584-Ab-2 | Anti-Cynomolgus/ Rhesus macaque USP13 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T07584-Ab-1/ GM-Tg-felg-T07584-Ab-2 | Anti-Feline USP13 monoclonal antibody | Feline |
| GM-Tg-cang-T07584-Ab-1/ GM-Tg-cang-T07584-Ab-2 | Anti-Canine USP13 monoclonal antibody | Canine |
| GM-Tg-bovg-T07584-Ab-1/ GM-Tg-bovg-T07584-Ab-2 | Anti-Bovine USP13 monoclonal antibody | Bovine |
| GM-Tg-equg-T07584-Ab-1/ GM-Tg-equg-T07584-Ab-2 | Anti-Equine USP13 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T07584-Ab-1/ GM-Tg-hg-T07584-Ab-2; GM-Tg-rg-T07584-Ab-1/ GM-Tg-rg-T07584-Ab-2; GM-Tg-mg-T07584-Ab-1/ GM-Tg-mg-T07584-Ab-2; GM-Tg-cynog-T07584-Ab-1/ GM-Tg-cynog-T07584-Ab-2; GM-Tg-felg-T07584-Ab-1/ GM-Tg-felg-T07584-Ab-2; GM-Tg-cang-T07584-Ab-1/ GM-Tg-cang-T07584-Ab-2; GM-Tg-bovg-T07584-Ab-1/ GM-Tg-bovg-T07584-Ab-2; GM-Tg-equg-T07584-Ab-1/ GM-Tg-equg-T07584-Ab-2 |
| Products Name | Anti-USP13 monoclonal antibody |
| Format | mab |
| Target Name | USP13 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-USP13 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T07584-Ag-1 | Recombinant multi-species UBP13/ USP13/ ISOT3 protein |
| ORF Viral Vector | vGMLP003180 | human USP13 Lentivirus particle |
| ORF Viral Vector | pGMLP003180 | human USP13 Lentivirus plasmid |
| ORF Viral Vector | pGMAD000031 | mouse Usp13 Adenovirus plasmid |
| ORF Viral Vector | vGMAD000031 | mouse Usp13 Adenovirus particle |
Target information
| Target ID | GM-T07584 |
| Target Name | USP13 |
| Gene ID | 8975,72607,310306,708624,478640,101091353,100141289,100065844 |
| Gene Symbol and Synonyms | 2700071E21Rik,IsoT-3,ISOT3,USP13 |
| Uniprot Accession | Q92995,E1BMF7 |
| Uniprot Entry Name | UBP13_HUMAN,UBP13_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000058056 |
| Target Classification | N/A |
The target: USP13, gene name: USP13, also named as ISOT3, IsoT-3. Enables several functions, including BAT3 complex binding activity; chaperone binding activity; and cysteine-type peptidase activity. Involved in several processes, including maintenance of unfolded protein involved in ERAD pathway; regulation of cellular catabolic process; and regulation of transcription, DNA-templated. Acts upstream of or within protein deubiquitination and protein stabilization. Predicted to be located in nucleoplasm. Predicted to be active in cytosol and nucleus. [provided by Alliance of Genome Resources, Apr 2022].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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