Anti-S23A2/ SLC23A2/ NBTL1 monoclonal antibody

Anti-S23A2/ SLC23A2/ NBTL1 antibody for FACS & in-vivo assay

Target products collectionGo to SLC23A2/SLC23A2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T08378-Ab-1/ GM-Tg-hg-T08378-Ab-2Anti-Human SLC23A2 monoclonal antibodyHuman
GM-Tg-rg-T08378-Ab-1/ GM-Tg-rg-T08378-Ab-2Anti-Rat SLC23A2 monoclonal antibodyRat
GM-Tg-mg-T08378-Ab-1/ GM-Tg-mg-T08378-Ab-2Anti-Mouse SLC23A2 monoclonal antibodyMouse
GM-Tg-cynog-T08378-Ab-1/ GM-Tg-cynog-T08378-Ab-2Anti-Cynomolgus/ Rhesus macaque SLC23A2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T08378-Ab-1/ GM-Tg-felg-T08378-Ab-2Anti-Feline SLC23A2 monoclonal antibodyFeline
GM-Tg-cang-T08378-Ab-1/ GM-Tg-cang-T08378-Ab-2Anti-Canine SLC23A2 monoclonal antibodyCanine
GM-Tg-bovg-T08378-Ab-1/ GM-Tg-bovg-T08378-Ab-2Anti-Bovine SLC23A2 monoclonal antibodyBovine
GM-Tg-equg-T08378-Ab-1/ GM-Tg-equg-T08378-Ab-2Anti-Equine SLC23A2 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T08378-Ab-1/ GM-Tg-hg-T08378-Ab-2; GM-Tg-rg-T08378-Ab-1/ GM-Tg-rg-T08378-Ab-2;
GM-Tg-mg-T08378-Ab-1/ GM-Tg-mg-T08378-Ab-2; GM-Tg-cynog-T08378-Ab-1/ GM-Tg-cynog-T08378-Ab-2;
GM-Tg-felg-T08378-Ab-1/ GM-Tg-felg-T08378-Ab-2; GM-Tg-cang-T08378-Ab-1/ GM-Tg-cang-T08378-Ab-2;
GM-Tg-bovg-T08378-Ab-1/ GM-Tg-bovg-T08378-Ab-2; GM-Tg-equg-T08378-Ab-1/ GM-Tg-equg-T08378-Ab-2
Products NameAnti-SLC23A2 monoclonal antibody
Formatmab
Target NameSLC23A2
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SLC23A2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species S23A2/ SLC23A2/ NBTL1 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLPm004435mouse Slc23a2 Lentivirus plasmid
    ORF Viral VectorvGMLPm004435mouse Slc23a2 Lentivirus particle


    Target information

    Target IDGM-T08378
    Target NameSLC23A2
    Gene ID9962,54338,50622,717939,403490,101101633,783536,100052186
    Gene Symbol and SynonymsmKIAA0238,NBTL1,SLC23A1,SLC23A2,SVCT2,YSPL2,YSPL3
    Uniprot AccessionQ9UGH3,Q9WTW8
    Uniprot Entry NameS23A2_HUMAN,S23A2_RAT
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000089057
    Target ClassificationN/A

    The target: SLC23A2, gene name: SLC23A2, also named as NBTL1, SLC23A1, SVCT2, YSPL2. The absorption of vitamin C into the body and its distribution to organs requires two sodium-dependent vitamin C transporters. This gene encodes one of the two required transporters and the encoded protein accounts for tissue-specific uptake of vitamin C. Previously, this gene had an official symbol of SLC23A1. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.