Anti-CD38/ ADPRC 1/ ADPRC1 monoclonal antibody

Anti-CD38/ ADPRC 1/ ADPRC1 antibody for FACS & in-vivo assay

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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Size： 1mg | 10mg | 100mg

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Target information

The target: CD38, gene name: CD38, also named as ADPRC 1, ADPRC1. The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015].

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